Clinical applications of Norian SRS (calcium phosphate cement) in craniofacial reconstruction in children: Our experience at Hospital La Paz since 2001

Gómez, Elena; Martín, Mercedes; Arias, Jesús de la Fuente; Carceller, Fernando

doi:10.1016/j.joms.2004.09.008

Cited by 53 publications

(43 citation statements)

References 26 publications

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“…All the cases of infection had exposure to the nasal or oral cavity. In the study by Gomez et al [30] they found one case of wound dehiscence with infection out of five cases treated for secondary craniofacial deformities. In a study of all cranioplasty cases undertaken at AIIMS, New Delhi from Jan 2008 to Apr 2010, they found 22.5 % complications out of 114 cases [25].…”

Section: Discussionmentioning

confidence: 98%

Cranioplasty of Hemispherical Defects Using Calcium Phosphate Cements Along with Titanium Mesh: Our Experience

Kumar

Sudeep

Balwan

2015

J. Maxillofac. Oral Surg.

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Introduction Cranial defects may arise due to trauma, infection, surgical ablation or errors in development. Restoration of such defects is important for esthetics, function and morale of the patient. Several materials are available. Each has its advantages and disadvantages. Search is on for an ideal material. Autogenous grafts remain the gold standard in reconstruction of such defects. However, the morbidity associated with their harvest, additional time required, the need for a second surgical site and the limited supply has led to the search for newer substitutes. Although many materials are available today including biologic and non biologic substitutes, there is still no consensus about the best material. In this article we describe our use of calcium phosphate cements for reconstruction of hemispherical cranial defects. Materials and Methods Cases requiring reconstruction of hemispherical cranial defects (more than 15 cm in any dimension) were selected for study. After exposing the defect under GA, titanium mesh was adapted to the defect for support. Then the calcium phosphate cement was prepared and injected on the mesh to establish good contour. The alloplastic insert in each patient was evaluated for: (a) Immediate post-operative complications (b) Restoration of contour and soft tissue support (c) New bone formation ascertained on HRCT at the end of 2 years. Patients were examined on postoperative first week, at 3 and at 6 months.High resolution computed tomography scans were taken at 2 years postop. There were two female and three male patients. Results There were no complications in the post operative period. The general condition of the patients improved post operatively. Even though the cements maintained their contour at 2 years, there were no signs of bone formation within the cement. Conclusion Calcium phosphate cement is a good bone substitute for use in cranioplasty. In defects requiring mechanical strength, it should be supported by a titanium mesh. It retains the contour but is not replaced by bone even after 2 years.

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Section: Discussionmentioning

confidence: 98%

Cranioplasty of Hemispherical Defects Using Calcium Phosphate Cements Along with Titanium Mesh: Our Experience

Kumar

Sudeep

Balwan

2015

J. Maxillofac. Oral Surg.

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“…Many alloplastic materials such as titanium A B 15) . To be an ideal cranioplasty material, the material should ideally feature the following characteristics : 1) good tissue compatibility, 2) the ability to be easily contoured, 3) stable through the patient's lifetime or if desorbed, replaced by structurally stabling bone without significant loss of volume or change in shape; 4) radiolucent to allow unimpeded computed tomography scanning of the intracranial contents, and 5) the ability to become ingrown by living tissue 5,7,18) . Until present, one of the most commonly used materials to repair the cranial bone defect is PMMA bone cement.…”

Section: Discussionmentioning

confidence: 99%

“…Titanium mesh and polymer cannot be easily formed or shaped 18) ; therefore, it is not easy to make satisfactory contouring in a complicated shape area, especially in the fronto-zygomatic-temporal area without special fixing elements. Calcium phosphate cement is highly biocompatible and is gradually replaced with autologous bone by osteoconduction 7) . Because of these characteristics, calcium phosphate cement has been used for the repair of craniofacial fractures in plastic and reconstructive surgeries 3,4,7,11,[17][18][19] .…”

Section: Discussionmentioning

confidence: 99%

“…Accompanying a negligible exothermic reaction, the CPCs provide structure integrity in hours. In addition, the minor exothermic nature of the CPC setting, together with the fact that no special fixation elements e.g., screws, miniplates or suture materials are needed to fix the CPC, makes this material ideal for craniofacial reconstruction 3,4,7,11,[17][18][19] . In this article, we report our clinical experience in repair and augmentation of bone defects to prevent postoperative temporal depression in several pterional craniotomy cases using a brushite CPC, PolyBone ® (Kyungwon Medical Co. Ltd., Seoul, Korea).…”

Section: Introductionmentioning

confidence: 99%

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Clinical Experience of the Brushite Calcium Phosphate Cement for the Repair and Augmentation of Surgically Induced Cranial Defects Following the Pterional Craniotomy

Ahn

2010

J Korean Neurosurg Soc

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Objective : To prevent temporal depression after the pterional craniotomy, this study was designed to examine the safety and aesthetic efficacy of the brushite calcium phosphate cement (CPC) in the repair and augmentation of bone defects following the pterional craniotomy. Methods : The brushite CPC was used for the repair of surgically induced cranial defects, with or without augmentation, in 17 cases of pterional approach between March, 2005 and December, 2006. The average follow-up month was 20 with range of 12-36 months. In the first 5 cases, bone defects were repaired with only brushite CPC following the contour of the original bone. In the next 12 cases, bone defects were augmented with the brushite CPC rather than original bone contour. For a stability monitoring of the implanted brushite CPC, post-implantation evaluations including serial X-ray, repeated physical examination for aesthetic efficacy, and three-dimensional computed tomography (3D-CT) were taken 1 year after the implantation. Results : The brushite CPC paste provided precise and easy contouring in restoration of the bony defect site. No adverse effects such as infection or inflammation were noticed during the follow-up periods from all patients. 3D-CT was taken 1 year subsequent to implantation showed good preservation of the brushite CPC restoration material. In the cases of the augmentation group, aesthetic outcomes were superior compared to the simple repair group. Conclusion : The results of this clinical study indicate that the brushite CPC is a biocompatible alloplastic material, which is useful for prevention of temporal depression after pterional craniotomy. Additional study is required to determine the long-term stability and effectiveness of the brushite calcium phosphate cement for the replacement of bone.

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“…Calcium phosphate cement has been successfully used in clinics as bone repair biomaterial for many years [31][32][33][34][35][36] . However, poor mechanical properties limit any further applications [37][38][39] .…”

Section: Discussionmentioning

confidence: 99%

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Torkittikul¹,

Chaipanich²

2009

ScienceAsia

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Biomaterials containing calcium silicate have been widely used in dental and bone repaired applications. This study investigated mechanical and in vitro biological properties of ordinary and white Portland cement both of which are composed mainly of calcium silicates. The time of setting was determined using a Vicat needle. Compressive strength was measured at the age of 1, 3, and 7 days. The 1 day set Portland cement pastes were soaked in a simulated body fluid to investigate the ability of the material to form a bond with living bone tissue. X-ray diffraction traces of samples following immersion in simulated body fluid demonstrated that both cement pastes form a hydroxyapatite layer within 7 days but white Portland cement shows a noticeably higher amount of apatite crystal than that of ordinary Portland cement. Scanning electron micrographs reveal a clear presence of hydroxyapatite on the surface of white, but not in ordinary Portland cement. In addition, white Portland cement can achieve a compressive strength of 30 MPa within 24 h after curing in distilled water at human temperature.

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Clinical applications of Norian SRS (calcium phosphate cement) in craniofacial reconstruction in children: Our experience at Hospital La Paz since 2001

Cited by 53 publications

References 26 publications

Cranioplasty of Hemispherical Defects Using Calcium Phosphate Cements Along with Titanium Mesh: Our Experience

Cranioplasty of Hemispherical Defects Using Calcium Phosphate Cements Along with Titanium Mesh: Our Experience

Clinical Experience of the Brushite Calcium Phosphate Cement for the Repair and Augmentation of Surgically Induced Cranial Defects Following the Pterional Craniotomy

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