Clinical Applications of CA 15–3

Do hydronephrosis and extracorporeal shock wave lithotripsy affect carbohydrate antigens?

“…These are either high molecular weight mucines or are blood group antigens. Apart from in the presence of tumoral diseases, they are also secreted by normal tissues [2,3].…”

“…ESWL results in histopathological changes in the tissue, biochemical changes in the serum and urine, and hormonal and hematological changes both in vitro and in vivo [1][2][3][4]. The effect of ESWL on carbohydrate antigens (CA) has not been investigated to date.…”

“…In general, during the follow-up of those patients, physicians will decide whether the cancer has recurred or not by using tumor markers as well as CT and MRI imaging. Assessment of the tumor markers in the serum is commonly used for malignancy [2][3][4] as it is simpler and cheaper than the other methods.…”

Marcadores Tumorais: Revisão de Literatura

“…A sensibilidade varia de acordo com a massa tumoral e o estadiamento clínico, sendo de 88% a 96% na doença disseminada 24 . Na fase inicial, apenas 23% dos casos apresentam aumento deste marcador 25 . Aumento superior a 25% na concentração do CA 15.3 correlaciona-se com a progressão da doença em 80% a 90% dos casos, e a diminuição em sua concentração está associada à regressão em 70% a 80% 3 .…”