Clinical Application of Ultrasound Guidance for Parametrial Treatment of Advanced Cervical Cancer

Abstract

Objectives-To evaluate the accuracy of ultrasound (US) in determining the positions of parametrial implants by comparing US with magnetic resonance imaging (MRI) for advanced cervical cancer.Methods-Patients undergoing brachytherapy with parametrial implantation for cervical cancer from February 2017 to February 2019 were involved in the study. The transverse section of the cervix (surface S 1 ) and the transverse section 1 cm above the external cervix (surface S 2 ) were selected from MRI and US images as the observation planes. In the MRI observation plane, the distances between the uterine titanium needles and the uterine tube/implanter were set as M 1 to M 4 ; in the US observation plane, the distances between the uterine titanium needles and the uterine tube/implanter were set as D 1 to D 4 . The differences and consistency in M and D of each group were then compared.Results-There were no significant differences between M and D in each group (P = .058; P = .821; P = .870; and P = .936, respectively). The intraclass correlation coefficients of M and D in each group were 0.970, 0.968, 0.952, and 0.956. A regression analysis showed that the relationships between M and D in each group were as follows: M 1 = 0.9449D 1 + 0.1812; M 2 = 0.9463D 2 + 0.0965; M 3 = 0.9176D 3 + 0.1233; and M 4 = 0.9253D 4 + 0.1224.Conclusions-In parametrial brachytherapy for cervical cancer, US can accurately determine the positions of parametrial implantation needles, which is already applicable on MRI, and can provide assistance in parametrial brachytherapy for advanced cervical cancer.