Clinical application of triangular parabolic PEEK mesh with hole button produced by combining CAD, FEM and 3DP into cranioplasty

Zhong, Rongde; Xie, Zuoming; Liao, Youhao; Li, Yunqing; Huang, Chi-Wen

doi:10.4066/biomedicalresearch.29-18-138

Cited by 2 publications

(3 citation statements)

References 31 publications

(40 reference statements)

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“…Specifically, intervertebral devices ( n = 3), 27,28,42 spinal clips designed for spinal fusion infection ( n = 2) 30,31 and cylindrical implants ( n = 1) 29 were evaluated in these six studies. Furthermore, AM PEEK/PEKK was investigated for cranio‐maxillofacial (CMF) implants and reconstructions in six studies 4,6,40,49,56,58 . Mandibular implant ( n = 1), 6 cranial implants ( n = 2), 4,49 disk samples ( n = 1), 40 and porous scaffolds ( n = 2) 56,58 were printed in these six studies via both SLS and FFF.…”

Section: Resultsmentioning

confidence: 99%

“…Furthermore, AM PEEK/PEKK was investigated for cranio‐maxillofacial (CMF) implants and reconstructions in six studies 4,6,40,49,56,58 . Mandibular implant ( n = 1), 6 cranial implants ( n = 2), 4,49 disk samples ( n = 1), 40 and porous scaffolds ( n = 2) 56,58 were printed in these six studies via both SLS and FFF. In total, four studies investigated AM PAEKs for dental applications.…”

Section: Resultsmentioning

confidence: 99%

“…As the precision and reliability of additive manufacturing (AM) advances, 3D printing of high temperature polymers is gaining increasing attention for biomedical applications, especially for production in a hospital setting 1‐3 . Polyetheretherketone (PEEK) and polyetherketoneketone (PEKK), two members of the polyarylketone (PAEK) family, have been increasingly investigated using AM, with the ultimate goal of providing personalized treatments by developing techniques suitable for implant applications 4‐6 . Unlike extensive research in AM of metallic biomaterials such as Ti‐6Al‐4V alloy in the past two decades, 7 considerably less is known about AM of PAEKs and the structure–property relationships and suitability for implantation of especially fused filament fabricated (FFF) PAEKs.…”

Section: Introductionmentioning

confidence: 99%

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Structure, properties, and bioactivity of 3D printed PAEKs for implant applications: A systematic review

et al. 2021

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Additive manufacturing (AM) of high temperature polymers, specifically polyaryletherketones (PAEK), is gaining significant attention for medical implant applications. As 3D printing systems evolve toward point of care manufacturing, research on this topic continues to expand. Specific regulatory guidance is being developed for the safe management of 3D printing systems in a hospital environment. PAEK implants can benefit from many advantages of AM such as design freedom, material and antibacterial drug incorporation, and enhanced bioactivity provided by cancellous bone‐like porous designs. In addition to AM PAEK bioactivity, the biomechanical strength of 3D printed implants is crucial to their performance and thus widely studied. In this review, we discuss the printing conditions that have been investigated so far for additively manufactured PAEK implant applications. The effect of processing parameters on the biomechanical strength of implants is summarized, and the bioactivity of PAEKs, along with material and drug incorporation, is also covered in detail. Finally, the therapeutic areas in which 3D printed PAEK implants are investigated and utilized are reviewed.

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