Clinical application of radiophotoluminescent glass dosimeter for dose verification of prostate HDR procedure

Abstract

High dose rate brachytherapy (HDR-BT) is one of the many modalities for prostate cancer treatment. Due to the nature of HDR-BT, in vivo dosimetry is feasible and can be used to verify consistent dose delivery. In order to validate a dose verification system for HDR-BT prostate cancer treatment, a radiophotoluminescent glass dosimeter (RPLGD) was used and the measurements were compared with those from a thermoluminescent dosimeter. The RPLGD shows many advantages in HDR-BT dose measurement, such as repeatability, stability, and small effective size. These advantages make the RPLGD a superior option for use as a dosimeter in HDR-BT. The results described here show that the difference between the measured dose and the treatment planned dose is less than 5%. A Monte Carlo simulation for the dose was performed using Monte Carlo N -particle to investigate position error. This study concludes that the RPLGD is a promising and reliable dosimeter for HDR-BT in vivo dosimetry with clinically acceptable accuracy.

Dose Distributions of an192Ir Brachytherapy Source in Different Media

“…The GD-301 dosimeter is composed of a rod glass element measuring 1.5 mm in diameter and 8.5 mm in length, and it must undergo heat treatment at 70°C for 1 hour before reading with the Dose Ace FGD-100 reader. The active readout size of the GD-301 dosimeter of 1 mm makes it a suitable tool for measuring brachytherapy sources with high dose gradients [16]. …”

A Study on the Dose Distributions in Various Materials from an Ir-192 HDR Brachytherapy Source

“…When the entrance angle was - 80°, the GD-301 response was 7% lower than that at 0°. This data can be explained by the radiophotoluminescence signal readout center of GD-301, which is 0.7 mm away from its edge and under such circumstance could result in radiation attenuation [18].…”

“…Dose readouts were performed with a FGD-1000 reader (Asahi Techno Glass). When set to the high-dose range, effective GD-301 dosimeter readout size was 1 mm in diameter and 0.6 mm deep [16], [17], making the GD-301 ideal for brachytherapy dose measurements [18].…”

Feasibility Study on Applying Radiophotoluminescent Glass Dosimeters for CyberKnife SRS Dose Verification

“…The glass dosimeter has a cylindrical shape and is 1.5 mm in diameter and 12 mm in length. The readout system used a 1 mm diameter pulsed UV laser as an excitation light source, and the visible light signal was then collected through the 0.6 mm reading window to evaluate the radiation dose [15]. …”