Clinical Application of Optical Coherence Tomography in the Corneal Degenerations

Abstract

Anterior segment optical coherence tomography (AS-OCT) has become an essential tool in the diagnosis and management of corneal degenerations. AS-OCT optical findings and thickness measurements are useful for the proper evaluation of the ocular surface diseases. AS-OCT imaging provides noninvasive information necessary to decide clinical and surgical management. This device helps to achieve a correct pre-intervention investigation and will allow physicians to compare the corneal status after the surgical process. Thus, it is useful to evaluate the corneal thickness, areas of hyper-reflective material, and corneal fibrosis in certain disorders such as Salzmann's nodular degeneration (SND) and Terrien's marginal degeneration (TMD), before and following the surgical process.

Correlation Between Slit Lamp (SL) Examination and Anterior Segment Optical Coherence Tomography (AS-OCT) for The Evaluation of Central Infectious Corneal Perforation

“…Higher axial resolution pictures were made possible by the advancement of OCT from time domain to spectral domain. A noninvasive, in vivo cross-sectional picture of the ocular surface and corneal structure can be obtained using AS-OCT devices, with resolutions ranging from less than 5 m (ultra-high-resolution) to greater than 5 m (high-resolution) [5].…”