Clinical and ultrasonological features of adenomyosis and its histopathological correlation

Gupta, Sunita; Goel, Gunjan; Agrawal, Surabhi; Garg, Prachi; Khanuja, Esha

doi:10.18203/2320-1770.ijrcog20163158

Cited by 2 publications

(1 citation statement)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[ 14 ] Our sensitivity and specificity both were lower when compared to that by Gupta et al . (89.13% and 90.62%),[ 13 ] perhaps due to the subjective nature of the diagnostic criteria of adenomyosis on TVS. A systematic review and meta-analysis carried out by Andres et al .…”

Section: Discussionmentioning

confidence: 99%

Diagnostic Role of Transvaginal Sonography and Magnetic Resonance Imaging in Adenomyosis of the Uterus and its Correlation with Histopathology

Jain

Kumar

Shukla

et al. 2023

Journal of Mid-Life Health

View full text Add to dashboard Cite

Background and Objective: The prevalence of adenomyosis of the uterus varies from 5% to 70%, and there is no clear consensus on its imaging diagnostic criteria. The objective of this study was to evaluate the role of transvaginal sonography (TVS), combined TVS and color Doppler (TVS-CD), and magnetic resonance imaging (MRI) in the diagnosis of adenomyosis. Materials and Methods: This was a tertiary care hospital-based prospective study, in which 365 clinically suspected cases of adenomyosis were enrolled. All three types of imaging (TVS, TVS-CD, and MRI) were done in 233/365 patients, followed by hysterectomy in 50. Imaging features were correlated with the histopathological examination (HPE), which was taken as the gold standard for the diagnosis. The diagnostic performance of each imaging modality was assessed. Results: Among patients who underwent hysterectomy, 36/50 (72%) had adenomyosis on HPE, with or without associated benign gynecological abnormalities. Sensitivity, specificity, positive predictive value (PPV), negative PV (NPV), and diagnostic accuracy (DA) of MRI were higher than that of TVS-CD (91.67% vs. 77.78%, 85.71% vs. 78.57%, 94.29% vs. 90.32%, 80% vs. 57.89%, and 90% vs. 78%, respectively). TVS alone had lower diagnostic performance (specificity: 64.29%, PPV 84.85%, NPV 52.94%, and DA74%) than TVS-CD, but equal sensitivity (77.78%). Heterogeneous myometrium was the most sensitive (80.56%), while myometrial cyst was the most specific (92.86%) TVS feature. The maximum junctional zone thickness ≥12 mm was the most sensitive (97.22%), while the hyperintense myometrial focus was the most specific (100%) MRI feature. Conclusion: TVS-CD should be used as an initial diagnostic imaging modality in clinically suspected cases of adenomyosis; however, MRI due to better diagnostic efficacy should be the imaging modality of choice before subjecting such patients to hysterectomy.

show abstract

Section: Discussionmentioning

confidence: 99%

Diagnostic Role of Transvaginal Sonography and Magnetic Resonance Imaging in Adenomyosis of the Uterus and its Correlation with Histopathology

Jain

Kumar

Shukla

et al. 2023

Journal of Mid-Life Health

View full text Add to dashboard Cite

show abstract

Role of Magnetic Resonance Imaging in Evaluation of Uterine Pathologies and Its Correlation With Ultrasound

AAYUSH BANSAL,

SIMMI BHATNAGAR,

MANOJ MATHUR

2023

Asian J Pharm Clin Res

View full text Add to dashboard Cite

Objective: Uterine pathologies, both benign and malignant, are common among reproductive age females and postmenopausal females. Herein, we aim to assess the role of magnetic resonance imaging (MRI) in the evaluation of uterine pathologies and to correlate them with ultrasonographic findings (USG). Methods: We conducted a prospective study in the Department of Radiodiagnosis at Government Medical College and Rajindra Hospital, Patiala. It included 45 females who were referred from department of obstetrics and gynecology with clinical suspicion of uterine pathologies. All the patients underwent both USG and MRI, results were compiled and statistical tests applied. Results: The mean (±SD) age of patients was 38.9±10.8 years. About 82% of the females were premenopausal. Nineteen females were diagnosed with fibroids, nine had adenomyosis, and two patients had endometrial polyps. Five of each were histopathologically proven cases of cervical and endometrial carcinoma. Four patients were diagnosed with Mullerian anomalies. MRI could diagnose more number of fibroids and in more number of patients. On USG, adenomyosis was falsely diagnosed in one patient and was reported as normal in one other patient. In cases of endometrial carcinoma, myometrial invasion was better predicted through MRI. Similarly, in cases of cervical carcinoma, parametrial extension was underdiagnosed by USG alone. MRI detected bicornuate bicollis uterus and septate uterus in two cases each. Very good correlation was observed between the USG and MRI findings with Kappa coefficient of 0.823 (p<0.001). Conclusion: MRI is the radiological imaging of choice in patients with suspected uterine pathologies and correlates well with USG. Therefore, USG and MRI should be combined together in case of diagnostic dilemma for better decision-making and patient management

show abstract

Clinical and ultrasonological features of adenomyosis and its histopathological correlation

Cited by 2 publications

References 24 publications

Diagnostic Role of Transvaginal Sonography and Magnetic Resonance Imaging in Adenomyosis of the Uterus and its Correlation with Histopathology

Diagnostic Role of Transvaginal Sonography and Magnetic Resonance Imaging in Adenomyosis of the Uterus and its Correlation with Histopathology

Role of Magnetic Resonance Imaging in Evaluation of Uterine Pathologies and Its Correlation With Ultrasound

Contact Info

Product

Resources

About