Clinical and Therapeutic Characteristics of Patients with Type 2 Diabetes Mellitus in Romania – Mentor Study

Abstract

Background and aims: PREDATORR Study estimated diabetes mellitus (DM) prevalence in Romania at 11.7%. MENTOR is the first national major study trying to determine the quality of the metabolic control in patients with type 2 diabetes (T2DM), the therapeutic options used, and the microvascular and macrovascular complications prevalence in order to achieve a better management for Romanian patients with T2DM. Material and methods: The study was designed as an observational analytical, multicenter, prospective study. Study population was selected from T2DM patients stratified by: age, diabetes duration and gender. Data was collected in an eCRF: demographics, physical examination, cardiovascular evaluation, blood tests, known pathology, treatment. Results: There were 54.80% women, mean age was 60.53±7.39 years. The average BMI is over 30 kg/m2 with a decreasing trend over the age. 60% had their HbA1c over the threshold of 7%. Average blood pressure was less than 140/80 mmHg. 76,66% of T2DM subjects have at least one chronic complication. On oral therapy we have 55.44% of patients, on insulin only therapy 12.99% and on a combination of oral and insulin therapy 22.51%. Conclusions: This study showed a high prevalence of diabetes complications and metabolic alterations (obesity, hypertension, dyslipidemia, etc.). Age, male gender and diabetes duration were associated with a higher risk for poor metabolic control and complications. Further data will be collected over a 3 years period to obtain a better image over T2DM evolution in Romanian population.

Death by SARS-CoV 2: a Romanian COVID-19 multi-centre comorbidity study

“…Moreover, Romania has a record number of deaths due to preventable causes like ischemic cardiac disease, pulmonary cancer or alcoholism 14 . The prevalence of diabetes is approximately 11.6% and doubles for prediabetes as confirmed by Predatorr study 15 and Mentor study 16 . Therefore, it is expected that a high number of infections with SARS-CoV-2 in Romania to have a severe course of the disease or to end deadly.…”

Death by SARS-CoV 2 - a Romanian COVID-19 multi-centre comorbidity study

“…[14]. The prevalence of diabetes is approximately 11.6% and doubles for prediabetes as con rmed by Predatorr study [15] and Mentor study [16]. Therefore, it is expected that a high number of infections with SARS-CoV-2 in Romania to have a severe course of the disease or to end deadly.…”

<p>Validation and cross-cultural adaptation of the depression Patient’s Health Questionnaire – 9 in the Romanian population of patients with Type 2 Diabetes Mellitus</p>

“…Alongside other more well-known complications or co-morbidities11 which are present in patients with T2DM, such as obesity, heart disease, sleep apnea or non-alcoholic fatty liver disease, depression is a frequent condition occurring in patients with T2DM 12,13. The presence of depression decreases both the overall prognosis of T2DM (mediated mainly through impaired adherence to diabetes-related self-management methods) and the patient’s quality of life, quality of life which is cited in many other chronic as well as acute diseases as revealed by several scoring instruments.…”