Clinical and serological aspects of visceral leishmaniasis in Northeast Brazilian dogs naturally infected with Leishmania chagasi

Almeida, Maria Ângela Ornelas de; Jesus, Erica Etelvina Viana de; Sousa-Atta, M.L.B.; Alves, Lêucio Câmara; Berne, M. E. A.; Atta, Ajax Mercês

doi:10.1016/j.vetpar.2004.10.010

Cited by 60 publications

(45 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Regarding the ELISA test, the lower sensitivity (43.6%) and specificity (86.3%) observed in our study, in comparison with others (QUINNELL et al, 1997(QUINNELL et al, , 2001REITHINGER et al, 2002;ALMEIDA et al, 2005;ROSÁRIO et al, 2005), may have been because we included all the samples collected over the entire period and not just single samplings. Methodological differences, such as the antigen and reagents used, are likely to have contributed to this difference as well.…”

Section: Discussioncontrasting

confidence: 75%

Serological, parasitological and molecular tests for canine visceral leishmaniosis diagnosis in a longitudinal study

Nunes

Lima

Melo

et al. 2015

Rev. Bras. Parasitol. Vet.

View full text Add to dashboard Cite

One of the measures to control visceral leishmaniosis (VL) in Brazil is the identification and culling of the canine reservoir. There is much controversy concerning this strategy, including the proper identification of positive dogs and the fact that the host-parasite relationship changes over time make it more challenging. A dynamic cohort of 62 dogs was followed every three months using serological and parasitological examinations and PCR. Positivity by PCR was higher than by serology and by parasitological examinations and showed a tendency to decrease over time, while serology tended to increase after six months. Concomitant positivity in all tests was observed in 10.4% of the samples, and negativity in 29.1%. Overall sensitivity ranged from 43.6 to 64.1%, and was not uniform over time. The proportion of dogs with or without clinical signs was not different by cytology or PCR but PCR was able to identify a larger number of asymptomatic dogs compared to ELISA and immunochromatography. PCR can be useful for surveillance of areas where cases of canine VL have not yet been detected and in which control strategies can be implemented to limit the spread of the disease. Despite the advance in diagnostic tools CVL diagnosis remains a challenge.

show abstract

Section: Discussioncontrasting

confidence: 75%

Serological, parasitological and molecular tests for canine visceral leishmaniosis diagnosis in a longitudinal study

Nunes

Lima

Melo

et al. 2015

Rev. Bras. Parasitol. Vet.

View full text Add to dashboard Cite

show abstract

“…Almeida et al 15 descreveram a esplenomegalia, hepatomegalia, onicogrifose e nefropatias, levando, estas últimas, às poliúria e polidipsia.…”

Section: Chagasiunclassified

Caracterização clínica e epidemiológica das leishmanioses em cães no Estado de São Paulo

Toscano

Rossi

Ribeiro

et al. 2013

Braz. J. Vet. Res. Anim. Sci.

View full text Add to dashboard Cite

ResumoCaracterizou-se retrospectivamente, a partir do ano de 1997 até março de 2008, a ocorrência de casos de leishmaniose, visceral ou tegumentar, dentre os cães dermatopatas atendidos em serviço especializado de hospital-escola veterinário AbstractThe occurrence of visceral or cutaneous canine leishmaniasis cases among dermatophatic dogs admitted to the veterinary teaching hospital School of Veterinary Medicine and Animal Husbandry -University of São Paulo from 1997 to 2008 was retrospectively characterized. For the diagnosis of 427 animals, serological (Enzyme-Linked Immunosorbent Assay, Indirect Immunofluorescence and/or Complement Fixation), parasitological and molecular (Polymerase Chain Reaction) tests were performed, which resulted in 117 (27.4%) confirmed positive cases. Of these, 96 (82.1%) were pure breed dogs and the others 21 (17.9%) were cross breed, being 57 (48.7%) females and 60 (51.3%) males. In terms of age, 26 (22.2%) were younger than 36 months, 48 (41%) were between 36 and 84 months, and 43 (36.8%) were older than seven years old. Sixty-four (54.7%) dogs were considered oligosymptomatic, 44 (37.6%) symptomatic, and the remaining nine (7.7%) asymptomatic. The main clinical findings were, in descending order, dermal lesions, lymphadenopathy, anemia, dysorexia, prostration and splenomegaly. As for hematological disorders, relative and absolute lymphopenia was the most important findings. Ninety-six (82.1%) of the positive animals correspond to allochthonus cases from São Paulo municipality.

show abstract

“…O cão tem sido implicado como principal hospedeiro e importante reservatório na cadeia epidemiológica da infecção em ambiente doméstico, cuja transmissão é dependente da população de Lutzomyia longipalpis (Paranhos-Silva et al, 1996;Almeida et al, 2005). Porém, em áreas silvestres e sinantrópicas, outros vertebrados como roedores, marsupiais, primatas e canídeos silvestres podem estar envolvidos no ciclo de transmissão da doença (Deane e Deane, 1955;Deane, 1956).…”

unclassified

Leishmaniose visceral canina no município de São Vicente Férrer, Estado de Pernambuco, Brasil

Silva

Braga

2008

RBCV

View full text Add to dashboard Cite

Clinical and serological aspects of visceral leishmaniasis in Northeast Brazilian dogs naturally infected with Leishmania chagasi

Cited by 60 publications

References 23 publications

Serological, parasitological and molecular tests for canine visceral leishmaniosis diagnosis in a longitudinal study

Serological, parasitological and molecular tests for canine visceral leishmaniosis diagnosis in a longitudinal study

Caracterização clínica e epidemiológica das leishmanioses em cães no Estado de São Paulo

Leishmaniose visceral canina no município de São Vicente Férrer, Estado de Pernambuco, Brasil

Contact Info

Product

Resources

About