Clinical and radiographic peri‐implant parameters and proinflammatory cytokine levels among cigarette smokers, smokeless tobacco users, and nontobacco users

Akram, Zohaib; Vohra, Fahim; Bukhari, Ishfaq A.; Sheikh, Saeed Ahmed; Javed, Fawad

doi:10.1111/cid.12575

Cited by 60 publications

(48 citation statements)

References 30 publications

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“…Numerous studies have investigated the effects of cigarette smoking on peri‐implant health and have reported significantly compromised peri‐implant parameters as compared with non‐smokers (NS) . These results have been confirmed by clinical laboratory investigations and have shown significantly high levels of proinflammatory cytokines in the peri‐implant sulcular fluid (PISF) of cigarette smokers (CS) as compared with NS …”

Section: Introductionmentioning

confidence: 85%

Proinflammatory cytokine levels and peri‐implant parameters among cigarette smokers, individuals vaping electronic cigarettes, and non‐smokers

ArRejaie

Al‐Aali

Alrabiah

et al. 2018

Journal of Periodontology

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108

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Background Tobacco smoking compromises the prognosis of dental implant treatment and is associated with increased risk of peri‐implant bone loss and increased implant failure rate. There is a dearth of studies that have compared clinical, radiographic, and immunological peri‐implant parameters among cigarette smokers (CS), individuals vaping e‐cigarettes (e‐cigs), and non‐smokers (NS). This study aimed to compare clinical and radiographic peri‐implant parameters and levels of matrix metalloproteinase (MMP)‐9 and interleukin (IL)‐1β levels among CS, individuals’ vaping e‐cigs, and NS. Methods Thirty‐two CS (group 1), 31 individuals vaping e‐cigs (group 2), and 32 NS (group 3) were included. Demographic‐ and implant‐related data were collected using a structured baseline questionnaire. Peri‐implant plaque index (PI), bleeding on probing (BOP), and probing depth (PD) were recorded and marginal bone loss (MBL) were assessed using standardized digital radiographs. Enzyme‐linked immunosorbent assay was used to assess levels of MMP‐9 and IL‐1β in peri‐implant sulcular fluid. Pearson correlation coefficient was used to analyze for correlations of MMP‐9 and IL‐1β levels with peri‐implant parameters. Results BOP showed significantly higher values in group 3 as compared with groups 1 and 2 (P < 0.01). PI (P < 0.01), PD ≥ 4 mm (P < 0.01), and mean concentrations of MMP‐9 (P < 0.001) and IL‐1β (P < 0.01) were significantly higher in groups 1 and 2 than group 3. MBL was significantly higher in group 1 as compared with group 2 and group 3 (P < 0.01). Significant positive correlations were found between MMP‐9 (P = 0.0198) and IL‐1β (P = 0.0047) levels and MBL in group 1; and a significant positive correlation between IL‐1β and MBL in group 2 (P = 0.0031). Conclusions Peri‐implant health was compromised among CS than vaping individuals and NS. Increased levels of proinflammatory cytokines in CS and vaping individuals may suggest greater peri‐implant inflammatory response.

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Section: Introductionmentioning

confidence: 85%

Proinflammatory cytokine levels and peri‐implant parameters among cigarette smokers, individuals vaping electronic cigarettes, and non‐smokers

ArRejaie

Al‐Aali

Alrabiah

et al. 2018

Journal of Periodontology

Self Cite

108

View full text Add to dashboard Cite

show abstract

“…32 This factor can negatively affect the osseointegration as well as survival/success of dental implants in subjects with CKD. According to Akram et al, 36 peri-implant soft tissue inflammation and CBL are higher around implants placed in tobacco-smokers and individuals using smokeless-tobacco products compared with individuals not using tobacco products. [33][34][35] We hypothesize that soft-tissue inflammation and CBL are significantly higher around adjacent implants placed in type-2 diabetic patients with other systemic diseases than patients with type-2 diabetes alone.…”

Section: Discussionmentioning

confidence: 99%

Peri‐implant soft tissue status and crestal bone levels around adjacent implants placed in patients with and without type‐2 diabetes mellitus: 6 years follow‐up results

Alasqah

Alrabiah

Al‐Aali

et al. 2018

Clin Implant Dent Rel Res

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“…17,18 Digital periapical radiographs were taken with paralleling technique using film holders. Radiographs were taken as described in our previous studies.…”

Section: Radiographic Evaluationmentioning

confidence: 99%

Clinical and radiographic peri‐implant outcomes of short dental implants placed in posterior jaws of patients with treated generalized aggressive periodontitis: A 3‐year follow‐up study

Akram

Vohra

Sheikh

et al. 2019

Clin Implant Dent Rel Res

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Background: Studies assessing clinical and radiographic peri-implant parameters around short dental implants (SDIs) in treated generalized aggressive periodontitis (GAgP) patients are scant.Objectives: This 3-year follow-up study aimed to compare the clinical peri-implant and radiographic bone status around SDIs placed in partially edentulous patients treated for GAgP and periodontally healthy patients and to assess the implant success rate between both the groups. Materials and Methods:A total of seven patients clinically diagnosed with GAgP and seven periodontally healthy patients was included in the clinical study. Forty-eight (29 maxilla; 19 mandible) and 11 (8 maxilla; 3 mandible) SDIs were placed in the GAgP group and healthy group, respectively. Plaque index (PI), bleeding on probing (BOP), probing depth (PD), and clinical attachment level (CAL) were recorded at six sites around all teeth and implants. Marginal bone loss (MBL) was studied incorporating in a specialized software and examined on a calibrated computer display screen with the help of an image analyzer. Patient satisfaction was recorded using a questionnaire sheet that contained questions regarding esthetics and function of the restorations. Results:The implant survival rate after 3 years was 81.25%. BOP and CAL around SDIs of GAgP patients were significantly higher than in periodontally healthy subjects (P = .01) throughout the follow-up. CAL around the teeth of GAgP patients was significantly greater during the follow-up than around the teeth of periodontal healthy subjects (P = .02). The PI and BOP between the teeth and implants showed no statistical significant difference. The mean PD at teeth was 0.4 mm greater than at implants. Implants showed significantly increased attachment loss than teeth (P = .01). The overall mean satisfaction of visual analogue scale was 12.8 ± 1.45.Conclusion: This short-term follow-up study indicates SDIs remain functionally stable in the posterior jaws of treated GAgP patients. K E Y W O R D Saggressive periodontitis, dental scaling, short dental implants, survival rate

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Clinical and radiographic peri‐implant parameters and proinflammatory cytokine levels among cigarette smokers, smokeless tobacco users, and nontobacco users

Abstract: Background: It is postulated that clinical and radiographic peri-implant parameters are worse and

Cited by 60 publications

References 30 publications

Proinflammatory cytokine levels and peri‐implant parameters among cigarette smokers, individuals vaping electronic cigarettes, and non‐smokers

Proinflammatory cytokine levels and peri‐implant parameters among cigarette smokers, individuals vaping electronic cigarettes, and non‐smokers

Peri‐implant soft tissue status and crestal bone levels around adjacent implants placed in patients with and without type‐2 diabetes mellitus: 6 years follow‐up results

Clinical and radiographic peri‐implant outcomes of short dental implants placed in posterior jaws of patients with treated generalized aggressive periodontitis: A 3‐year follow‐up study

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