Clinical and Radiographic Investigation of the Adjunctive Effects of a Low-Power He-Ne Laser in the Treatment of Moderate to Advanced Periodontal Disease: A Pilot Study

Lai, S.M.L.; Zee, Kwan-Yat; Lai, M.K.; Corbet, EF

doi:10.1089/pho.2007.2206

Cited by 32 publications

(60 citation statements)

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“…In a case-control study, LLLT add on therapy improved not significantly oral health in terms of PD reduction, but it resulted in a significantly higher reduction in bleeding scores compared to non surgical treatment alone. 24 Moreover, in a split-mouth study Lai et al 25 The present study has, in our opinion, some limitations. First, the small sample size.…”

Section: Discussionmentioning

confidence: 66%

Low Laser Therapy Plus Non-Surgical Periodontal Treatment Reduces Interleukin-1 Beta Serum Levels

Franceschi

Giudice

Pacifico

et al. 2016

JDOI

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Objectives: Periodontal disease is associated to widespread systemic inflammation, and further to both cardiovascular morbidity and mortality. Data from intervention studies demonstrated the beneficial effects of periodontal therapy in reducing vascular diseases. The present study was aimed to explore whether low-level Laser therapy as an adjunct to scaling and root planning reduces serum levels of inflammatory cytokines. Material and Methods:Thirty patients were enrolled. All recruited participants underwent blood sampling and dental inspection for periodontal indexes measurement. Plaque index, gingival index and probing depth were employed as measures of periodontal disease. Afterwards, patients underwent scaling and root planning plus low-level Laser therapy. Inflammatory biomarkers and periodontal indexes were measured before treatment and twenty weeks after treatment.Results: Plaque index, gingival index and probing depth largely improved at the follow-up visit, resulting more than halved from the baseline. Furthermore, a significant reduction of serum interleukin-1 beta has been observed (1.1 [SD 2.1] vs 0.5 [SD 1.3], P = 0.04), whereas serum interleukin-6 levels remained substantially unchanged. Blood C-reactive protein levels decreased at the follow-up, but not reaching statistical significance.Conclusions: therapy addressed to a local improvement of periodontal disease gives a reduction of systemic inflammation, possibly beneficial for cardiovascular health. D e n t a l a n d O r a l I m p l a n t s

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Section: Discussionmentioning

confidence: 66%

Low Laser Therapy Plus Non-Surgical Periodontal Treatment Reduces Interleukin-1 Beta Serum Levels

Franceschi

Giudice

Pacifico

et al. 2016

JDOI

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“…No papers on Flower Therapy were included because we found no RCT about this CIP. The use of CIP was predominantly associated with the treatment of periodontal disease (ANDERSEN et al, 2007;ANGELOV et al, 2009;CARUSO et al, 2008;DE ANDRADE et al, 2008;DE OLIVEIRA et al, 2007DERDILOPOULOU et al, 2007;GEORGE et al, 2009;JAIN et al, 2008;KAMMA et al, 2009;KELBAUNSKIENE et al, 2007;LAI et al, 2009;LOPES et al, 2010;MOMMOLO et al, 2008;MUÑOZ et al, 2001;OZCELIK et al, 2008;POLASNKSY et al, 2009;QADRI et al, 2005;RASSAMEEMASMAUNG et al, 2007;RIEGER et al, 2002;RODRIGUES et al, 2009;SASTRAVAHA et al, 2003;SCHWARZ et al, 2001;SIGUSCH et al, 2010;TING et al, 2007), different types of orofacial pain FACCO et al, 2008;GODDARD et al, 2002;KATSOULIS et al, 2001KATSOULIS et al, , 2010KITADE;OHYABU, 2000;MAZZETTO et al, 2007;MICHALEK-SAUBERER et al 2007;MOUSAVI et al, 2009a and b;POHODENKO-CHUDAKOVA, 2005;SCHMID-SCHWAP et al, 2006;SIMMA et al, 2009;SMITH et al, 2007;TORTAMANO et al, 2009;VENÂNCIO et al, 2005) and reduction in biofilm formation (AL TEEN et al, 2006;…”

Section: Resultsmentioning

confidence: 99%

“…The 'split mouth design' was used in some researches analyzed in this review (ASSAF et al, 2007;CARUSO et al, 2008;DERDILOPOULOU et al, 2007;DE OLIVEIRA et al, 2007;KAMMA et al, 2009;KELBAUSKIENE;MACIULSKIENE, 2007;LAI et al, 2009;LOPES et al, 2010;MUMMOLO et al, 2008;OZCELIK et al, 2008;PEREIRA et al, 2010;QADRI e tal., 2005;RODRIGUES et al, 2009;SCHWARZ et al, 2001;ZEZELL et al, 2009). We detected the 'split mouth design' as complicating factor to planning, conducting and analyzing the result of RCTs, especially in studies evaluating the use of CIP.…”

Section: Resultsmentioning

confidence: 99%

<b>The use of complementary and integrative practices in oral health

Gonçalo

Barros

2014

Acta Sci. Health Sci.

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ABSTRACT. The World Health Organization recognizes the medical practices derived from the culture of each country, as Traditional Medicine, but all over the world, there has been no consensus about the denomination of these practices. In Brazil, the Ministry of Health recognizes the use of the following, as Complementary and Integrative Practices (CIP): Acupuncture, Homeopathy, Medicinal Plants/Phytotherapy, Thermal Water/Crenotherapy, Anthroposophic Medicine. Based on the therapies recognized by the Ministry of Health, the Brazilian Federal Council of Dentistry regulated the use of CIP in oral health: Acupuncture, Homeopathy, Phytotherapy, Laser Therapy, Flower Therapy and Hypnosis. This article presents the results of a systematic review about positive and negative evidence of the use of PIC in oral health. We analyzed 91 papers published between 2000 and 2010. Laser therapy and Phytotherapy were the CIP most tested. Laser therapy studies reported more negative results, while the Phytotherapy studies reported more positive results. Papers on Flower Therapy were not included because we found no RCT about this CIP. We found more positive than negative outcomes for the use of CIP in oral health and analysis of the papers showed that only a few authors reported the clinical outcomes. Due to the holistic perspective of CIP, we believe it is possible to show more consistent results of use of these practices in oral health, provided that a broader view (beyond quantitative parameters) is incorporated from the planning to analysis of studies in this area.Keywords: review, complementary therapies, dentistry.O uso das práticas integrativas e complementares na odontologia RESUMO. A Organização Mundial de Saúde reconhece como medicina tradicional as práticas médicas derivadas da cultura de cada país, porém, não há consenso sobre a denominação de tais práticas. No Brasil, o Ministério da Saúde reconhece como Práticas Integrativas e Complementares (PIC): Acupuntura, Homeopatia, Plantas Medicinais/Fitoterapia, Termalismo/Crenoterapia, Medicina Antroposófica. Com base nas terapias reconhecidas pelo Ministério da Saúde, o Conselho Federal de Odontologia regulamentou o uso das PIC: Acupuntura, Homeopatia, Fitoterapia, Laserterapia, Terapia Floral e Hipnose. Este artigo apresenta e discute resultados de uma revisão sistemática sobre evidências positivas e negativas do uso das PIC em saúde bucal. Foram analisados 91 artigos publicados entre 2000 e 2010. Laserterapia e Fitoterapia foram as PIC mais testadas. Constatou-se mais resultados negativos sobre Laserterapia e mais resultados positivos sobre Fitoterapia. Artigos sobre Terapia Floral não foram incluídos porque não foram encontrados estudos clínicos controlados randomizados sobre esta PIC. Houve predominância de resultados positivos e poucos autores relataram a significância clínica das intervenções. Acredita-se que é possível mostrar resultados mais consistentes sobre o uso das PIC em saúde bucal, a partir de uma visão mais ampla (além de parâmetros quantitativos) assumida d...

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“…12 Contrary to our findings, Lai et al suggested that low-power laser did not result in any additional clinical benefit. 13 This might be a result of their application power density being low (2.83 mW/cm 2 ) and having limited application sites. The use of different kinds of lasers, doses, and duration preclude a comparison of these studies with our study.…”

Section: Discussionmentioning

confidence: 99%

A Randomized Controlled Microbiological Trial on Efficacy of Photodynamic and Low-Level Laser Therapies As An Adjunct To Nonsurgical Treatment of Chronic Periodontitis

2015

IJDA

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Clinical and Radiographic Investigation of the Adjunctive Effects of a Low-Power He-Ne Laser in the Treatment of Moderate to Advanced Periodontal Disease: A Pilot Study

Abstract: Within the limits of this pilot study, the use of the low-power He-Ne laser as an adjunct to non-surgical periodontal therapy in patients with moderate to advanced chronic periodontitis did not seem to provide additional clinical benefit.

Cited by 32 publications

References 40 publications

Low Laser Therapy Plus Non-Surgical Periodontal Treatment Reduces Interleukin-1 Beta Serum Levels

Low Laser Therapy Plus Non-Surgical Periodontal Treatment Reduces Interleukin-1 Beta Serum Levels

<b>The use of complementary and integrative practices in oral health

A Randomized Controlled Microbiological Trial on Efficacy of Photodynamic and Low-Level Laser Therapies As An Adjunct To Nonsurgical Treatment of Chronic Periodontitis

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