Clinical and Radiographic Evaluation of Simultaneous Alveolar Ridge Augmentation by Means of Preformed Titanium Meshes at Dehiscence-Type Peri-Implant Defects: A Prospective Pilot Study

Abstract

Background: bone augmentation by means of manually shaped titanium mesh is an established procedure to regenerate atrophic alveolar ridges and recreate a proper contour of the peri-implant bone anatomy. Conversely, current literature on the use of preformed titanium meshes instead of traditional grids remains lacking. Therefore, the aim of the present prospective study was to evaluate the use of preformed titanium mesh to support bone regeneration simultaneously to implant placement at dehiscence-type defects from clinical, radiological, and patient-related outcomes. Methods: 8 implants showing buccal dehiscence defects were treated with preformed titanium mesh directly fixed to flat abutments screwed to the implant. Intrasurgical clinical measurements and radiographic evaluations by means of cone-beam computed tomography scans were performed to assess the horizontal bone gain after 8 months from the augmentation surgery. Biological and patient-centered outcomes were also evaluated.; Results: clinically, a mean horizontal bone gain of 4.95 ± 0.96 mm, and a mean horizontal thickness of the buccal plate of 3.25 ± 0.46 mm were found. A mean horizontal bone gain of 5.06 ± 0.88 mm associated with a mean horizontal thickness of the buccal plate of 3.45 ± 0.68 mm were observed radiographically. From a macroscopic aspect, the remodeled graft appeared well integrated with the host bone. Well vascularized newly formed bone-like tissue was observed in intimate contact with the implants. Conclusions: preformed titanium mesh may be effective in supporting simultaneous horizontal bone regeneration at dehiscence-type peri-implant defects. Titanium mesh exposure still remain an issue in this type of surgery.

Effects of metformin on the osteogenesis of alveolar BMSCs from diabetic patients and implant osseointegration in rats

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With the development of oral implant technology and materials, dental implant therapy has become a highly effective method for the recovery of normal chewing function and aesthetics in partially and totally edentulous patients (De Angelis et al, 2017;Maiorana et al, 2020). However, the presence of systemic diseases such as T2DM in some patients is considered to be a relative contraindication to implant therapy (Mombelli & Cionca, 2006).In the past two decades, the number of diabetic patients has increased considerably in China and is projected to more than double from 20.8 million in 2000 to 42.3 million in 2030 (Boutayeb & Boutayeb, 2005).

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The effect of bone defect size on the 3D accuracy of alveolar bone augmentation performed with additively manufactured patient-specific titanium mesh

“…Therefore, installation and retention during clinical operations still depend on the surgeon's judgment of the anatomical position. Furthermore, placing 3D-printed patient-specific titanium meshes at the defect site, with and without bone graft, is very different [31,32]. Part of the anatomical landmarks covered by the bone mixture can hinder the positioning of the titanium mesh in the correct position to a certain extent, resulting in the movement or misalignment of titanium mesh [33].…”

Evaluation of Vertical Bone Augmentation Using a Titanium Ring Retained in Simultaneous Implants With Early Exposure: A Pilot Study in Dogs

“…Similar results can be observed with titanium mesh. It is thought that when vertical ridge augmentation is performed, the risk of exposure of the titanium mesh is high [38][39][40] . Early exposure of the bone graft to the oral cavity and exposure occurring within 4 weeks after bone augmentation have been identi ed as reasons for infection and bone graft loss, and the soft tissue associated with in ammation remains in place and impedes the ingrowth of bone even after the resolution of the in ammation 17,41 .…”