Clinical and psychosocial functioning in adolescents and young adults with anorectal malformations and chronic idiopathic constipation

Abstract

FI and constipation are major determinants of poor QoL in adolescents and young adults with ARMs and in those with CIC.

PeristeenⒸ Transanal Irrigation System for Paediatric Faecal Incontinence: A Single Centre Experience

“…Chronic constipation can also occur secondary to neuropathic bowel dysfunction due to spina bifida or traumatic spinal cord injuries. CIC has a considerable effect on a patient's psychological and emotional well-being and as such has a substantial impact on patient quality of life [4, 5]. Patients will often have long-term laxative regimes and may require suppositories, behavioural therapy, and sometimes surgical procedures such as manual evacuations, rectal biopsies, and the Malone antegrade continence enema [6].…”

Prevalence of Active Long-term Problems in Patients With Anorectal Malformations: A Systematic Review

“…[13][14][15][16][17][18][19][20][21][22][23][24] there were no published randomized clinical trials on the topic. there was 1 prospective controlled study, 13 1 retrospective cohort study, 14 and 10 cross-sectional survey studies [15][16][17][18][19][20][21][22][23][24] (table 1). the studies were conducted at a broad range of medical and surgical centers in sweden, 13 singapore, 14 Germany, 15 14,17,18,20 seven studies, with a total of 308 patients, analyzed the prevalence of chronic constipation, which ranged from 22.2% to 86.7%.…”

“…the studies were conducted at a broad range of medical and surgical centers in sweden, 13 singapore, 14 Germany, 15 14,17,18,20 seven studies, with a total of 308 patients, analyzed the prevalence of chronic constipation, which ranged from 22.2% to 86.7%. 13,14,17,[20][21][22]24 the largest study (n = 59) reported a prevalence of 33.9% (95% Ci, 23.0%-46.8%). 24 in the studies that included adults only, the reported prevalence of chronic constipation ranged from 26.9% to 33.9% (n = 118).…”

“…the most common active problems identified by the authors were fecal incontinence (16.7%-76.7%), chronic constipation (22.6%-86.7%), urinary incontinence (1.7%-30.5%), ejaculatory dysfunction (15.6%-41.2%), and erectile dysfunction (5.6%-11.8%). [13][14][15][16][17][18][19][20][21][22][23][24] there was a reduction in the overall prevalence of active medical problems in the adult group compared with the teenagers.…”

“…Demographics and quality scoring of included studies for meta-analysis[13][14][15][16][17][18][19][20][21][22][23][24] …”