Clinical and Psychological Characteristics of Patients with Globus

Bouchoucha, Michel; Rompteaux, Pierre; Bejou, Bakhtiar; Airinei, Gheorghe; Raynaud, Jean‐Jacques; Bénamouzig, Robert

doi:10.1016/s0016-5085(17)32419-8

Cited by 1 publication

(1 citation statement)

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“…In a prospective evaluation of 104 patients with globus, as many as 35% had anxiety disorder, and 13% had depression; 18% had borderline anxiety, while 28% had borderline depression 40 . Anxiety and hypochondriasis scores are higher in globus patients compared to those without this symptom, 41 and in urban residents compared to rural residents 42 . Both anxiety and depression appear to be more prevalent in females 40 .…”

Section: Etiology Of Globusmentioning

confidence: 87%

ESNM/ANMS Review. Diagnosis and management of globus sensation: A clinical challenge

Zerbib

Rommel

Pandolfino

et al. 2020

Neurogastroenterology Motil

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Globus is a non‐painful sensation of a tightness or a lump/foreign body in the throat that is not associated with dysphagia and may actually improve during meals. While several otorhinolaryngologic, thyroid, and esophageal disorders have been linked to globus, cause‐and‐effect relationships are difficult to establish. Consequently, though part of the evaluation, objective otorhinolaryngologic and esophageal testing is often negative. The presence of alarm symptoms, particularly pain, weight loss, dysphagia, or odynophagia is indications for objective testing. A diagnosis of idiopathic globus requires exclusion of pharyngeal, laryngeal, and esophageal disorders with laryngoscopy, endoscopy, high‐resolution manometry, barium radiography, and/or ambulatory reflux monitoring. A trial of acid‐suppressive therapy may be reasonable in the absence of alarm symptoms, especially if concurrent reflux symptoms are identified. Ablation of heterotopic gastric mucosa in the proximal esophagus has been reported to improve globus symptoms. Beyond these specific approaches, further management of idiopathic globus consists of reassurance, neuromodulators, and complementary approaches. Globus has a benign course with no long‐term consequences, and the overall prognosis is good as the magnitude of symptoms may decline over time.

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Section: Etiology Of Globusmentioning

confidence: 87%