Clinical and Physiological Studies on Chronic Bronchitis

Simonsson, Bo G.

doi:10.1111/j.1398-9995.1965.tb03047.x

Cited by 2 publications

(1 citation statement)

References 17 publications

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“…They have usually been described as 'peripheral pools' (Simon and Galbraith, 1953) if smooth-walled and circular, and as 'spiders' (Reid, 1955;Freimanis and Molnar, 1960), or floral forms (Simon, 1958;Duinker and Huizinga, 1962) if irregular in outline. Their pathological basis has variously been ascribed to chronic bronchitis (Christopherson, 1933;Reid and Simon, 1959;Duinker and Huizinga, 1962;Gregg and Trapnell, 1969), centrilobular emphysema (Simon and Galbraith, 1953;1 .eopold and Seal, 1961;Leopold and Gough, 1963;Duinker and Huizinger, 1962;Nakamura et al, 1969;Heard, 1969;Blumenthal and Greenberg, 1972;Gamsu and Nadel, 1973;Thurlbeck, 1976) or bronchiolectasis (obliterative or otherwise) (Reid, 1955;Wisoff, 1958;Simonsson, 1965). In postmortem bronchograms Reid (1955) and Heard (1969) have shown radio-opaque material pooled in dilated bronchioles whose nor-mal diameter is less than 1 mm.…”

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confidence: 99%

Peripheral pooling of bronchographic contrast material: evidence of its relationship to smoking and emphysema.

Musk¹,

Gandevia²,

Palmer³

1978

Thorax

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. Peripheral pooling of bronchographic contrast material: evidence of its relationship to smoking and emphysema. Sixty-six subjects, mainly derived from various occupational groups and one-third of whom admitted to dyspnoea on exertion, have been grouped according to the appearance of their peripheral airways at bronchography with oily propyliodone. Eleven subjects showed marked peripheral pooling of radiographic contrast material, 22 showed mild or moderate pooling, and in 33 peripheral pools were absent. Pooling was not seen in non-smoking subjects. In the group of subjects without pooling, pulmonary function in non-smokers and subjects with a history of smoking was similar. Subjects with marked pooling had a significantly lower pulmonary diffusing capacity (transfer factor) and evidence of loss of pulmonary elastic recoil when compared with subjects with absent peripheral pooling. These results indicate that bronchographic peripheral pooling is associated with the physiological changes of panacinar pulmonary emphysema and suggest that a causal relationship may exist between the organic bronchiolar lesion of pooling and the peripheral parenchymal lesion of panacinar emphysema.

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