Clinical and Personality Profiles and Survival in Patients With COPD

Kumar, Ashutosh; Haldipur, C. V.; Boucher, Michael

doi:10.1378/chest.111.1.95

Cited by 28 publications

(16 citation statements)

References 9 publications

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“…Indeed, patients with COPD specified coping as a relevant component of health status 20. Previously, psychological distress and difficulty in coping with their disease has been shown to impact mortality in patients with severe COPD 21. Therefore, self-regulation could significantly assist participants to control their individual symptoms and avoid acute exacerbations 22.…”

Section: Discussionmentioning

confidence: 99%

One-year change in health status and subsequent outcomes in COPD

Wilke

Jones

Müllerová

et al. 2015

Thorax

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Section: Discussionmentioning

confidence: 99%

One-year change in health status and subsequent outcomes in COPD

Wilke

Jones

Müllerová

et al. 2015

Thorax

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“…The development of psychological sequelae in conjunction with physical illness is recognized to have an impact on subsequent outcomes of care 26 . No previous studies have investigated the association of psychological distress with frequent hospital admissions for AECOPD.…”

Section: Discussionmentioning

confidence: 99%

Frequent hospital readmissions for acute exacerbation of COPD and their associated factors

et al. 2006

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“…Our finding that moderate to severe depressive symptoms are associated with 3-year mortality is consistent with studies that found that depressive symptoms measured during 8 or shortly after 9 a hospitalization for COPD were associated with risk of death. In a small study 10 of 16 outpatients with COPD, the Minnesota Multiphasic Personality Inventory findings correlated with 4-year mortality. Two other studies 11,12 found an increased risk of mortality with emotional function measured using quality-of-life instruments but did not specifically assess depressive symptoms.…”

Section: Commentmentioning

confidence: 93%

Sex, Depression, and Risk of Hospitalization and Mortality in Chronic Obstructive Pulmonary Disease

et al. 2007

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Background:We sought to determine whether depressive or anxiety symptoms are associated with chronic obstructive pulmonary disease (COPD) hospitalization or mortality. These data were collected as part of the National Emphysema Treatment Trial (NETT), a randomized controlled trial of lung volume reduction surgery vs continued medical treatment conducted at 17 clinics across the United States between January 29, 1998, and July 31, 2002.Methods: Prospective cohort study among participants in the NETT with emphysema and severe airflow limitation who were randomized to medical therapy. Primary outcomes were 1-and 3-year mortality, as well as COPD or respiratory-related hospitalization or emergency department visit during the 1-year follow-up period. Of 610 patients randomized to medical therapy, complete data on hospitalization and mortality were available for 3 years of follow-up for 603 patients (98.9%).Results: Depressive symptoms were assessed using the Beck Depression Inventory (BDI) questionnaire, and anxi-ety was assessed using the State-Trait Anxiety Inventory. Among 610 subjects, 40.8% had at least mild to moderate depressive symptoms. Patients in the highest quintile of BDI score (BDI score, Ն15) had an increased risk of respiratory hospitalization in unadjusted analysis compared with patients in the lowest quintile (BDI score, Ͻ5) (odds ratio [OR], 2.26; 95% confidence interval [CI], 1.30-3.93). After adjustment for disease severity, this relationship was no longer statistically significant. The adjusted risk of 3-year mortality was increased among those in the highest quintile of BDI score (OR, 2.74; 95% CI, 1.42-5.29) compared with those in the lowest quintile. Anxiety was not associated with hospitalization or mortality in this population.Conclusions: Depressive symptoms are common in patients with severe COPD and are treated in few subjects. Depressive symptoms are associated with increased risk for 3-year mortality but not 1-year mortality or hospitalization.

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Clinical and Personality Profiles and Survival in Patients With COPD

Cited by 28 publications

References 9 publications

One-year change in health status and subsequent outcomes in COPD

One-year change in health status and subsequent outcomes in COPD

Frequent hospital readmissions for acute exacerbation of COPD and their associated factors

Sex, Depression, and Risk of Hospitalization and Mortality in Chronic Obstructive Pulmonary Disease

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