Clinical and pathological features of Xantogranulomatous Pyelonephritis: Single centre experience over 5 years

Petca, R.; Popescu, R.; Petca, Aida; Medar, Cosmin; Mitrache, L; Petrescu, A; Predoiu, G.; Danau, R.; Braticevici, B.; Jinga, Viorel

doi:10.1016/s1569-9056(17)32088-2

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“…We conducted a retrospective observational study from January 2013 to December 2017 that identified 29 patients diagnosed with XGP histologically confirmed who have been treated in our clinic (9). Moreover, patients with Xanthogranulomatous pyelonephritis associated with renal carcinoma have also been included.…”

Section: Methodsmentioning

confidence: 99%

Xanthogranulomatous pyelonephritis: presentation and management

Petca¹,

Popescu²,

Mareș³

et al. 2019

JMMS

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Xanthogranulomatous pyelonephritis (XGP) is characterized by the presence of lipidladen foamy macrophages with both acute and chronic phase inflammatory cells. The aim of the study is to present our experience about patients with Xanthogranulomatous pyelonephritis. 29 patients were evaluated through a complete anamnesis and the preoperative management included routine blood and biochemical tests, urine culture and renal ultrasound, intravenous urography and computed tomography (CT). All patients underwent open nephrectomy followed by the pathological exam. The main symptoms of these patients were fever and flank pain. Preoperative laboratory tests revealed anemia, leukocytosis and increasing levels of blood urea nitrogen (BUN) and creatinine. Kidney failure was noticed in almost half of the cases. This study succeeded to evaluate the demographic, clinical, biological, surgical and histological characteristics. A pathological diagnosis is mandatory mainly for the evaluation of its coexistence with renal carcinoma.

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Section: Methodsmentioning

confidence: 99%