Clinical and pathological aspects of condyloma acuminatum – review of literature and case presentation

Diţescu, Damian; Istrate-Ofiţeru, Anca-Maria; Roşu, Gabriela-Camelia; Iovan, Larisa; Liliac, Ilona Mihaela; Zorilă, George Lucian; Bălăşoiu, Maria; Cercelaru, Liliana

doi:10.47162/rjme.62.2.03

Cited by 17 publications

(17 citation statements)

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“…Keratotic papules lesion can grow solitary or in clusters to form a cauliflower shape. Most of these skin lesions are accompanied by itching, burning and pain, but can also be asymptomatic (Diţescu et al, 2021;Loo et al, 2019). The diagnosis of GCA can be made from the history and physical examination and the skin lesions that are same with the characteristic of the disease.…”

Section: Discussionmentioning

confidence: 99%

Electrosurgery on Giant Condyloma Acuminata

Dharsono

Setyowatie²

2023

J.Ilm.Kedokt. Wijaya Kusuma

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Giant Condyloma Acuminata (GCA) is a sexually transmitted infection caused by Human papillomavirus (HPV) types 6 and 11. GCA lesions can growth up to 10 cm and form like a cauliflower shape. This infection can affect patient’s quality of life. The goal of therapy in GCA is to remove all skin lesions, which can be done by surgical treatment. Many modalities have been tested in GCA cases, one of which is electrosurgery. The aim of this study was to evaluate effectiveness of electrosurgery for GCA. A 43-year-old woman came with complaints of warts appeared in the genital area since 3 months before. Examination showed multiple papules with a verrucous surface, size around 7 cm in the labia majora, labia minor and perineum. The acetowhite examination and histopathology lead to the diagnosis of condyloma acuminata. Electrosurgery (electrodesication) to remove GCA lesions divided into 2 times. Post-operative evaluation, patient did not complain of pain and erythema, edema, and pus. Electrosurgery is a therapeutic modality that can be chosen in cases of GCA. Electrosurgery, like other surgical modalities, is capable of removing the entire lesion, but the advantages of electrosurgery include not injuring large areas, minimal bleeding and a lower recurrence rate when compared to other therapeutic modalities.

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Section: Discussionmentioning

confidence: 99%

Electrosurgery on Giant Condyloma Acuminata

Dharsono

Setyowatie²

2023

J.Ilm.Kedokt. Wijaya Kusuma

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“…[8] CA is treated using topical agents (podophyllotoxin, imiquimod cream, or sinecatechins), by destructive or surgical treatments (trichloroacetic acid, cryotherapy, CO 2 laser ablation, or surgery), or by systemic interferon treatment. [6][7][8][9] Only 3 cases of coexistent CA and EMPD have been reported. [10][11][12] Here, we report a rare case of coexistent EMPD and CA.…”

Section: Introductionmentioning

confidence: 99%

“…[6] CA is usually asymptomatic, though this depends on lesion size and anatomical location, but can be pruritic or painful. [6][7][8][9] Clinically, CA is usually encountered as a papillomatous eruption in genital mucosa and is usually diagnosed by visual inspection. Only rarely is its diagnosis confirmed by biopsy.…”

Section: Introductionmentioning

confidence: 99%

“…treatments for CA focus on wart removal rather than eradicating the underlying viral infection. [8] CA is treated using topical agents (podophyllotoxin, imiquimod cream, or sinecatechins), by destructive or surgical treatments (trichloroacetic acid, cryotherapy, CO 2 laser ablation, or surgery), or by systemic interferon treatment. [6][7][8][9] Only 3 cases of coexistent CA and EMPD have been reported.…”

Section: Introductionmentioning

confidence: 99%

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Coexistence of condyloma acuminatum and extramammary Paget’s disease on penis and scrotum: A rare case report

Kang

Lee

et al. 2022

Medicine

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Rationale: Extramammary Paget’s disease (EMPD) is a rare skin cancer that commonly occurs in sites rich in apocrine glands, such as perineum, vulva, axilla, scrotum, and penis. On the other hand, condyloma acuminatum (CA; also referred to as anogenital warts) is a common benign neoplasm caused by human papillomavirus. Few cases of coexistent EMPD and CA have been reported because of the rarity of the condition. Patient concerns and diagnosis: A 72-year-old man with a genital mass, which appeared to be composed of multiple papillomatous masses, was referred for surgical resection. The lesion was first noticed 6 months previously and grew rapidly. CO2 ablative laser therapy was performed twice at a primary clinic, but the mass recurred. Intervention and outcomes: Excisional biopsy revealed the presence of coexistent EMPD and CA. Additional wide excision was performed, and postoperative biopsy confirmed no residual tumor. Two years after surgery, no recurrence had occurred. Lessons: CA can co-occur with several types of skin malignancies, and a skin malignancy coexisting with CA is difficult to diagnose visually. Therefore, even if a skin lesion in the genital region is considered to be CA, we recommend punch biopsy before treatment because it can benefit prognosiss.

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“…Indeed, none of them is usually typified by follicular hyperkeratosis on histopathology, while they show capillary dilation in papillary dermis, thus explaining the dermoscopic overlap when it comes to the vascular pattern. 6,7,8 Importantly, it has been taken into account that CL may manifest with different morphologies (e.g. crusted, verrucous and ulcerated), with possible variability of dermoscopic presentation.…”

mentioning

confidence: 99%

Dermoscopy of condyloma lata: An observational controlled study

Errichetti,

Lallas,

Galvan

2023

Aust J Dermatology

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Clinical and pathological aspects of condyloma acuminatum – review of literature and case presentation

Cited by 17 publications

References 100 publications

Electrosurgery on Giant Condyloma Acuminata

Electrosurgery on Giant Condyloma Acuminata

Coexistence of condyloma acuminatum and extramammary Paget’s disease on penis and scrotum: A rare case report

Dermoscopy of condyloma lata: An observational controlled study

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