Clinical and neurological features of the course and cognitive impairment in orthostatic hypotension in patients with neurodegenerative diseases

Слободін, Т.М.; Goreva, Ganna; Golovchenko, Yuriy; Klymenko, O.V.

doi:10.15587/2519-4798.2017.116733

Cited by 2 publications

(1 citation statement)

References 7 publications

(16 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In Postural Orthostatic Tachycardia Syndrome (POTS or SPOT), there is an excessive increase in HR (i.e., greater than 130 bpm) both at the beginning and during most of the tilt, usually with a mild hypotensive response. The psychogenic response occurs in the presence of symptoms of pre-syncope or syncope without significant hemodynamic changes to justify it and is called pseudo-syncope 8,9 .…”

Section: Methodsmentioning

confidence: 99%

The Tilt Test in the Assessment of Syncope and Pre-syncope. Effective and safe? Analysis of a Series of 2364 Patients over 6 Years

Rocha,

Kubrusly,

Gurgel

et al. 2024

J. Cardiac Arrhythmias

View full text Add to dashboard Cite

The tilt table test (TT) provides relevant information about individual susceptibility to neuro-mediated hypotension and bradycardia. Its importance has been questioned. In this work, we analyze the results and safety of TT in the investigation of syncope, presyncope or postural dizziness. Cross-sectional study, with TT exams performed by specialists in cardiac arrhythmias, in the period 2016-2021, in a syncope unit. Analyzes were performed using the Mann-Whitney test, multiple logistic regression, with a significant p value <0.05. The protocols used were Westminster or Italian protocol. There were 2364 TT performed, 61.7% female, aged 51.1 (31-71) years. The positivity rate was 32.6%, 37.2% with pharmacological sensitization (p< 0.01). For the investigation of syncope, positivity was 34.2% (477) x 30.65% (285) for other symptoms (p<0.001), while evaluating syncope and presyncope together the difference was 37.55% (623) x 20.9% (139) for other symptoms (p<0.001). Positivity was higher in males (p<0.01; OR=1.40(1.16-1.69)), in sensitized tests (p<0.01;2.01(1.64-2, 38)), in patients with early orthostatic hypotension (OH) with symptoms (p <0.01; 9.68(4.13-27.44)). The complication rate was 3.29%, but without severity. The TT remains an important and safe methodology in clinical practice for the investigation of patients with suspected neurally mediated syndromes.

show abstract

Section: Methodsmentioning

confidence: 99%