Clinical and morphological aspects of laryngeal cysts

Abstract

To our knowledge only a few defined studies have been carried out on laryngeal cysts. These cysts represent a mixed group of benign laryngeal lesions that can cause diagnostic and therapeutic difficulties. The aim of this study was to characterize their histological structure and localizations in the larynx as well as to discuss theories about their genesis. Between 1973 and 1996, 342 laryngeal cysts were treated at Phillips University of Marburg, while from 1990 to 1996, 74 were treated at Justus Liebig University of Giessen. In all, 416 laryngeal cysts were treated by endolaryngeal microsurgery. All clinical charts were reviewed retrospectively and surgical specimens examined histomorphologically. Findings showed that 58.2% of the laryngeal cysts were located in the glottic area and 18.3% in the ventricular folds. The remainder were located on the aryepiglottic fold (2.2%) and interarythenoid region (0.7%). Two congenital cysts were also treated. Approximately 56% of the laryngeal cysts were lined by squamous cell epithelium, 37% by respiratory epithelium and 7% by oncocytic epithelium. In general, the laryngeal cysts were found to be a collection of inhomogenous lesions from different histogenetic origins with diverse symptoms related to their site and size. On the basis of our investigations, a new classification was established concerning the genesis and development of laryngeal cysts by subdividing cysts into congenital cysts, retention cysts, and inclusion cysts.

Quiste de vallécula como causa de estridor congénito: Reporte de un caso y revisión de la literatura

“…Posteriormente aparecen descripciones basadas en la histomorfología, como la de Newman BH y cols en 1984 y la de Ramesar K y Albizzati C en 1988; donde los clasifican en epiteliales, tonsilares y oncocíticos [18][19] . Fue Arens y cols en 1997 quien propone una nueva clasificación basada en la localización e histomorfología del quiste, clasificándolos como quistes congénitos, de retención y de inclusión 20 . Por último, Forte y cols en 2004 propusieron un nuevo sistema de clasificación para los quistes laríngeos congénitos con un enfoque terapéutico.…”

Vallecular Cysts in Adult Population: Ten Year Experience

“…The peak incidence in adults is seen in 5 th and 6 th decade and majority of the patients are males. 4,5 The symptoms vary depending upon the age of the patient, site of the cyst and size of the cysts. In neonatal period the cysts have been reported to cause noisy and labored breathing along with feeding difficulties.…”

Oncocytic variant of a ductal retention cyst in the interarytenoid region

“…Though on histopathology the cysts of these two anatomical sites have similarity, vallecular cysts should be classified separately. Laryngeal cysts present with hoarseness, foreign body sensation, dysphagia and, rarely , stridor 1,6,7 . Cysts in the interarytenoid region may be an incidental finding but may cause dysphagia if there is an inferior extension or if they arise from the post cricoid region.…”

“…Majority of laryngeal cysts present in the glottic area followed by the ventricular folds and the aryepiglottic folds 1 . Retention cysts are an abnormal dilatation of mucous glands which are numerous in the commonly affected ventricle and ventricular folds.…”