“…Nevertheless, these are based on heterogeneous populations of patients with prosthetic joint infection [8,[10][11][12], arthritis due to non-pyogenic microorganisms [5,6,8,12], and arthritis without a bacteriological diagnosis [9,10,12]. Moreover, some reports [9,11,12] have failed to distinguish between IVDUs and non-drug users and others include a scarce number of patients [6,7]. As a result, certain clinical, diagnostic, and therapeutic issues are yet to be clarified.…”