Clinical and Laboratory Profile of Dengue Viral Infections in and around Mangalore, India

Magnitude, Seasonal-variation, Serological and Hematological Profile of Dengue in a Tertiary Teaching Hospital, Karwar, India

“…This may be because increased awareness among our treating physicians and general public about the disease which gives rise to increased test requests. 2,6 A male preponderance of (67%) with the gender ratio being 2:1 was noted which was similar to a study done by T Damodar et al 2,19 When it comes to age distribution, most of them infected belonged to the age between 11 and 50. Other studies also mention that adults were more affected than children and elderly population.…”

“…A highly significant association between positive NS1 antigen and presentation of fever with less than 5 days duration is seen in the present study as depicted in Table 6 which is comparable to results of the study from Mangalore. 2 The present study had thrombocytopenia in 16% of cases when compared to the studies done by T Damodar et al and Ritu Karoli et al they claimed to have 72% and 89% respectively. 2,13 This study had few cases of leucopenia (28.6%) when compared to 86% of the same in a study by Ritu Karoli et al This difference might be because the present study had very less numbers of secondary cases.…”

“…Accordingly, every fever of unknown origin or undifferentiated fever case should be suspected as dengue unless proved otherwise especially during its peak season. 2 In the present study 1,550 patients were suspected of dengue infection, however only 157 (10.1%) was diagnosed of dengue infection. In a study by Goswami et al, 5 the percentage of dengue infection (20%) is a little higher compared to this study.…”

“…1 Population explosion, poor waste management, lack of proper drainage systems, migration, globalization, rapid urbanization, deforestation are the few reasons that dengue has made its place as one of the fastest emerging viral infections. 2 In India dengue is one of the top endemic viral diseases. 3 Its incidence exhibits seasonal variation.…”

“…1,[4][5][6] Dengue has a wide variety of clinical manifestations because of which the clinicians should have high suspicion especially during the above season. 2 According to WHO guidelines it is classified into dengue without warning signs, dengue with warning signs and severe dengue which includes dengue hemorrhagic fever and dengue shock syndrome. 7 As there are no effective vaccines or specific antiviral drugs available, the successful strategy to tame dengue lies in timely and rapid detection of cases, case management and vector control.…”