“…In childhood brucellosis cohort studies, the majority of cases have generally been older children. 6,[17][18][19] Although children of all ages are susceptible to brucellosis, our sample properly reflected the age distribution of childhood brucellosis. 6,7 In our cohort, boys were more frequently diagnosed with brucellosis than girls.…”
Section: Discussionmentioning
confidence: 99%
“…Most research has focused only on a small number of children with OA brucellosis, and reports of the frequency of OA complications and their specific sites of involvement have varied in these studies. 2,4,6,9,10,12,14,[17][18][19] The variation in reported frequencies may be because of local or age-related differences, which appear to play a role in the incidence, pattern and presentation of OA brucellosis in children. 1,2,9,13,17,20 The primary objective of this study was to evaluate the epidemiologic, demographic, and clinical characteristics, and laboratory and radiologic findings of children with brucellosis who presented to our pediatric infectious diseases department.…”
mentioning
confidence: 99%
“…Most research has focused only on a small number of children with OA brucellosis, and reports of the frequency of OA complications and their specific sites of involvement have varied in these studies. 2,4,6,9,10,12,14,17–19 The variation in reported frequencies may be because of local or age-related differences, which appear to play a role in the incidence, pattern and presentation of OA brucellosis in children. 1,2,9,13,17,20…”
Backgrounds:
Brucellosis is a systemic zoonotic disease. Osteoarticular (OA) system involvement is a common complication and the predominant manifestation of brucellosis in children. We aimed to evaluate the epidemiologic, demographic, clinical characteristics, and laboratory and radiologic findings of children with brucellosis and how these related to OA involvement.
Methods:
This retrospective cohort study consisted of all consecutive children and adolescents diagnosed as having brucellosis who were admitted to the pediatric infectious disease department of University of Health Sciences Van Research and Training Hospital between August 1, 2017, and December 31, 2018, in Turkey.
Results:
A total of 185 patients diagnosed as having brucellosis were evaluated, 50.8% had OA involvement (n = 94). Seventy-two patients (76.6%) exhibited peripheral arthritis involvement, among of them, hip arthritis (63.9%; n = 46) was the most common manifestation, followed by arthritis of knee (30.6%; n = 22), shoulder (4.2%; n = 3) and elbow (4.2%; n = 3). A total of 31 patients (33.0%) had sacroiliac joint involvement. Seven patients (7.4%) had spinal brucellosis. Erythrocyte sedimentation rate level above 20 mm/h at admission and age were independent predictor of OA involvement (respectively odds ratio [OR] = 2.82; 95% confidential interval [CI] = 1.41–5.64, ORperyear = 1.10; 95% CI: 1.01–1.19). Increasing age was associated types of OA involvement.
Conclusion:
A half of brucellosis cases had OA involvement. These results can help physicians to make early identification and diagnosis of childhood OA brucellosis who present with arthritis and arthralgia to enable the disease to be treated in time.
“…In childhood brucellosis cohort studies, the majority of cases have generally been older children. 6,[17][18][19] Although children of all ages are susceptible to brucellosis, our sample properly reflected the age distribution of childhood brucellosis. 6,7 In our cohort, boys were more frequently diagnosed with brucellosis than girls.…”
Section: Discussionmentioning
confidence: 99%
“…Most research has focused only on a small number of children with OA brucellosis, and reports of the frequency of OA complications and their specific sites of involvement have varied in these studies. 2,4,6,9,10,12,14,[17][18][19] The variation in reported frequencies may be because of local or age-related differences, which appear to play a role in the incidence, pattern and presentation of OA brucellosis in children. 1,2,9,13,17,20 The primary objective of this study was to evaluate the epidemiologic, demographic, and clinical characteristics, and laboratory and radiologic findings of children with brucellosis who presented to our pediatric infectious diseases department.…”
mentioning
confidence: 99%
“…Most research has focused only on a small number of children with OA brucellosis, and reports of the frequency of OA complications and their specific sites of involvement have varied in these studies. 2,4,6,9,10,12,14,17–19 The variation in reported frequencies may be because of local or age-related differences, which appear to play a role in the incidence, pattern and presentation of OA brucellosis in children. 1,2,9,13,17,20…”
Backgrounds:
Brucellosis is a systemic zoonotic disease. Osteoarticular (OA) system involvement is a common complication and the predominant manifestation of brucellosis in children. We aimed to evaluate the epidemiologic, demographic, clinical characteristics, and laboratory and radiologic findings of children with brucellosis and how these related to OA involvement.
Methods:
This retrospective cohort study consisted of all consecutive children and adolescents diagnosed as having brucellosis who were admitted to the pediatric infectious disease department of University of Health Sciences Van Research and Training Hospital between August 1, 2017, and December 31, 2018, in Turkey.
Results:
A total of 185 patients diagnosed as having brucellosis were evaluated, 50.8% had OA involvement (n = 94). Seventy-two patients (76.6%) exhibited peripheral arthritis involvement, among of them, hip arthritis (63.9%; n = 46) was the most common manifestation, followed by arthritis of knee (30.6%; n = 22), shoulder (4.2%; n = 3) and elbow (4.2%; n = 3). A total of 31 patients (33.0%) had sacroiliac joint involvement. Seven patients (7.4%) had spinal brucellosis. Erythrocyte sedimentation rate level above 20 mm/h at admission and age were independent predictor of OA involvement (respectively odds ratio [OR] = 2.82; 95% confidential interval [CI] = 1.41–5.64, ORperyear = 1.10; 95% CI: 1.01–1.19). Increasing age was associated types of OA involvement.
Conclusion:
A half of brucellosis cases had OA involvement. These results can help physicians to make early identification and diagnosis of childhood OA brucellosis who present with arthritis and arthralgia to enable the disease to be treated in time.
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