Clinical and Histopathological Comparative Study of Two Equine-Derived Bone Grafts: A Human Study

Adiloğlu, Selen; Giray, C. B.; Kulaç, İbrahim; Usubütün, Alp; Aktaş, Alper

doi:10.5455/jpma.296194

Cited by 1 publication

(1 citation statement)

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“…This evidence has been corroborated by the clinical success of these biomaterials, which confirmed the histologic and histomorphometric findings and showed an intimate apposition of newly formed bone in contact with the porous porcine-derived biomaterials, especially in maxillary sinus augmentation procedures [ 28 , 85 , 89 , 90 , 93 , 97 , 99 , 100 , 101 , 110 , 111 , 116 , 117 , 119 ].…”

Section: Discussionsupporting

confidence: 64%

A Narrative Review on the Effectiveness of Bone Regeneration Procedures with OsteoBiol® Collagenated Porcine Grafts: The Translational Research Experience over 20 Years

Romasco

Tumedei

Inchingolo

et al. 2022

JFB

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Over the years, several bone regeneration procedures have been proposed using natural (autografts, allografts, and xenografts) and synthetic (i.e., metals, ceramics, and polymers) bone grafts. In particular, numerous in vitro and human and animal in vivo studies have been focused on the discovery of innovative and suitable biomaterials for oral and maxillofacial applications in the treatment of severely atrophied jaws. On this basis, the main objective of the present narrative review was to investigate the efficacy of innovative collagenated porcine bone grafts (OsteoBiol®, Tecnoss®, Giaveno, Italy), designed to be as similar as possible to the autologous bone, in several bone regeneration procedures. The scientific publications were screened by means of electronic databases, such as PubMed, Scopus, and Embase, finally selecting only papers that dealt with bone substitutes and scaffolds for bone and soft tissue regeneration. A total of 201 papers have been detected, including in vitro, in vivo, and clinical studies. The effectiveness of over 20 years of translational research demonstrated that these specific porcine bone substitutes are safe and able to improve the biological response and the predictability of the regenerative protocols for the treatment of alveolar and maxillofacial defects.

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