Clinical and histopathological analysis of oral squamous cell carcinoma in young people

Ribeiro, Ana Carolina Prado; Santos‐Silva, Alan Roger; Simonato, Lorenzo; Salzedas, Leda Maria Pescinini; Sundefeld, Maria Lúcia Marçal Mazza; Soubhia, Ana Maria Pires

doi:10.1016/j.bjoms.2008.05.004

Cited by 59 publications

(90 citation statements)

References 19 publications

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“…Almost all the patients presented with multiple symptoms & 76.66% of the patients complain of soreness or irritation in the oral cavity, 70% complain of ulceration in the oral cavity, 60% complain of difficulty in mastication, 56.68% foul breath, 26.66% mild pain in the lesion, 23.33% Spitting of blood, 20% excessive salivation, 23.33% Dysphagia and odynophagia which is almost equal with other studies 5,6,7 In this study it was found that 60% of the lesions were ulcerative in type followed by 36.66% exophytic and 33% infiltrative in nature. The figures are in similarity with that found by Martinez-Conde-R et al 8 .…”

Section: Discussionsupporting

confidence: 49%

Clinicopathological study of oral Carcinoma

Kamal

Yousuf

Haider³

et al. 2015

Bangladesh J of Otorhinolaryngology

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Section: Discussionsupporting

confidence: 49%

Clinicopathological study of oral Carcinoma

Kamal

Yousuf

Haider³

et al. 2015

Bangladesh J of Otorhinolaryngology

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“…In a study conducted by Ribeiro et al and Soudry et al there was a high prevalence of oral cancer at advanced TNM stages. 7,8 In a similar study conducted by Hellen-Bandeira et al, there were 60.5% cases in Stage III and stage IV. 21 This clearly indicates lack of awareness amongst the subjects and aggressive nature of the condition such that most of the subjects present at advanced stage of the disease.…”

Section: Discussionmentioning

confidence: 69%

“…In today's time there are 4% to 13% of the cases of oral squamous cell carcinoma that affects subjects younger than 45 years of age. [4][5][6][7][8][9][10] The most frequently affected site is tongue and it is seen generally amongst alcohol and tobacco users. 4,5 Squamous cell carcinoma of lower lip is generally seen amongst subjects with exposure to sunlight.…”

Section: Introductionmentioning

confidence: 99%

“…9,[11][12][13][14][15] Oral squamous cell carcinoma occurring amongst the younger individuals have an increased aggressiveness and poor clinical prognosis when compared to those affecting the elderly subjects. 6,7,12,16,17 The prognosis of the condition is determined by the prognostic factors that would in turn determine the biological aggressiveness of the condition amongst the subjects. The various prognostic factors include regional lymph node metastasis, location of tumor and TNM classification.…”

Section: Introductionmentioning

confidence: 99%

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Clinical findings and risk factors associated with oral cancer: a prospective study

Gupta¹,

Singh²,

Bedi³

et al. 2018

Int J Otorhinolaryngol Head Neck Surg

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Background: Oral cancer is associated with high morbidity and mortality and therefore it represents a grave health problem worldwide. However there is scarcity of the studies in the literature regarding the prognostic factors amongst the subjects. The aim of the present study is to determine the various risk factors and the most commonly affected sites by the oral squamous cell carcinoma amongst subjects of different age groups. Methods: The present prospective comparative study was conducted at the Department of Radiotherapy at Guru Gobind Singh Medical College and Hospital during a period of three months i.e. from April 2016 to June 2016. Patients were evaluated every week for a period of approximately 2 weeks. Examination of the oral cavity was done using probe and mouth mirror by trained personnel. TNM classification was used to classify tumour. Patient’s habits like alcohol and tobacco intake were also recorded. Complete demographic information was obtained from all the patients. All the data thus obtained was arranged in a tabulated form and analysed using SPSS software. Results: The study included a total of 60 subjects. There were 11 females in the study and 49 males in the study. There were 18.3% (n=11) subjects having cancer of tongue. There were 23.3% (n=14) subjects having cancer of buccal mucosa. Alveolar ridge carcinoma was seen in 8.3% (n=5) subjects. There were 22 patients (30%) having stage III carcinoma. Majority of the subjects i.e. 70% (n= 38) were at stage IV A according to TNM classification. Conclusions: From the above study we can conclude that there is lack of awareness amongst the people about oral cancer. They mostly present during advanced stage of the disease. Most of the subjects are males, showing there predisposition towards harmful habits.

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“…Au niveau clinique, la localisation gingivale devient la plus fréquente [5]. L'évolution clinique se démarque du carcinome épidermoïde de l'adulte avec une tendance à l'invasion métastatique significativement plus élevée même si on ne retrouve pas de différence au niveau des grades histologiques [5,6]. Le pronostic est beaucoup plus sombre chez les moins de 30 ans avec, en cas de récidive, 100 % de décès à 16 mois [7] contre 12 à 50 % de survie à 5 ans selon les études chez l'adulte plus âgé [8].…”

Section: Discussionunclassified

Découverte d’un carcinome épidermoïde du trigone rétromolaire chez un jeune adulte sans facteurs de risque

Benhamou

Raybaud

Poissonnet

et al. 2014

Med Buccale Chir Buccale

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Résumé -Introduction :Le carcinome épidermoïde oral est habituellement diagnostiqué chez des patients alcoolo-tabagiques entre 50 et 60 ans. Des cas de carcinomes épidermoïdes oraux sont de plus en plus rapportés chez des patients jeunes sans facteurs de risques habituels, entrainant une errance diagnostique et un mauvais pronostic. Observation : Le diagnostic tardif d'un carcinome épidermoïde mandibulaire survenu chez un jeune patient de 27 ans sans facteurs de risque est rapporté. En dépit d'un traitement chirurgical, d'une chimiothérapie ciblée, et d'une radiothérapie, le patient n'a pas survécu. Discussion : L'interprétation des informations cliniques pourrait aider à comprendre ce qui provoque l'apparition prématurée de ces cancers et leur agressivité.Abstract -Discovery of squamous cell carcinoma of the retromolar trigone in a young adult without risk factors. Introduction: Oral squamous cell carcinoma (OSCC) is usually diagnosed in a context of alcohol and tobacco intoxication in patients between 50 and 60 years of age. Cases of OSCC are increasingly found in young patients without any of the usual risk factors, resulting in diagnostic uncertainty and poor prognosis. Case report: This article reports a case of late diagnosis of mandibular OSCC in a young 27-year-old male patient with no risk factors. Despite surgical treatment combined with targeted chemotherapy and radiotherapy, the patient did not survive. Discussion: Interpretation of clinical data might help in understanding what underlies early development of these cancers and their aggressiveness.

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Clinical and histopathological analysis of oral squamous cell carcinoma in young people

Cited by 59 publications

References 19 publications

Clinicopathological study of oral Carcinoma

Clinicopathological study of oral Carcinoma

Clinical findings and risk factors associated with oral cancer: a prospective study

Découverte d’un carcinome épidermoïde du trigone rétromolaire chez un jeune adulte sans facteurs de risque

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