Clinical and Histological Evaluation of Tissue Healing in Beveled or Perpendicular Vertical Releasing Incision

Sabeti, Mohammad; Moeintaghavi, Amir; Shiezadeh, Farid; Sedigh, Hamideh Salari; Tay, Ronney; Torabinejad, Mahmoud

doi:10.1016/j.joen.2021.07.005

Cited by 4 publications

(6 citation statements)

References 16 publications

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“…Thermo-plasticized gutta percha technique is not recommended for the tooth with periapical lesion and open apex, without apical barrier matrix because of wide apical foramen and uncontrolled length of working distance [ 1 , 10 , 16 , 17 , 28 ]. Once the apical plug of MTA has been established, any obturation techniques could have been performed to fill the remaining space of the root canal.…”

Section: Discussionmentioning

confidence: 99%

“…Both MTA and PRF are popular in dentistry. However, MTA is very popular, while PRF is less popular than the former in endodontics [ 10 , 17 , 18 ]. PRF is encountered mostly in surgical therapy, such as oral surgery, periodontal open flap management, and implant procedures [ 13 , 26 ].…”

Section: Discussionmentioning

confidence: 99%

“…By introducing platelet-rich fibrin (PRF) [ 9 ], especially the new form of PRF, A-PRF+, this strong fibrin membrane enriched with platelets and growth factors can be manipulated commonly in periodontology, implantology, oral surgery, and nonsurgical endodontic therapy [ 10 ]. PRF used in root canal therapy focuses on the application for regenerative endodontic procedure, which could not ensure in complete root formation, and modest reduction of root fracture opportunity [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

“…PRF is characterized by the relative centrifugal forces (RCFs) and has to being used for proper purposes [ 12 , 13 ]. Up to now, the investigations in PRF application for teeth with open apices are limited, and focused only on the conventional PRF [ 10 , 14 – 18 ]. The PRF showed good biocompatibility and promising results when it was combined with the MTA [ 6 , 11 , 15 , 17 , 19 ].…”

Section: Introductionmentioning

confidence: 99%

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Platelet-rich fibrin as an apical barrier for MTA placement in the treatment of teeth with open apices: a pilot study

Pham,

Pham

et al. 2024

J Transl Med

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Objective The aim of the present pilot study was to assess the effectiveness of the platelet-rich fibrin (PRF) apical barrier for the placement of MTA for the treatment of teeth with periapical lesions and open apices. Methods A total of thirty teeth on twenty-eight patients with open apices and periapical periodontitis were enrolled and divided into two groups in the present pilot study. In the PRF group (fourteen teeth in thirteen patients), nonsurgical endodontic treatment was performed using PRF as an apical matrix, after which the apical plug of the MTA was created. For the non-PRF group (fourteen teeth in fourteen patients), nonsurgical endodontic therapy was performed using only the MTA for an apical plug with no further periapical intervention. Clinical findings and periapical digital radiographs were used for evaluating the healing progress after periodic follow-ups of 1, 3, 6, and 9 months. The horizontal dimension of the periapical lesion was gauged, and the changes in the dimensions were recorded each time. The Friedman test, Dunn-Bonferroni post hoc correction, and Mann-Whitney U test were used for statistical analysis, with P < 0.05 serving as the threshold for determining statistical significance. Results All patients in both groups in the present pilot study had no clinical symptoms after 1 month, with a significant reduction in the periapical lesion after periodic appointments. The lesion width of the PRF group was significantly smaller than that of the non-PRF group in the sixth and ninth month after treatment. Conclusions PRF is a promising apical barrier matrix when combined with MTA for the treatment of teeth with open apices and periapical periodontitis. Small number of study subjects and the short time of follow-up period limit the generalizability of these results. Trial registration TCTR, TCTR20221109006. Registered 09 November 2022 - Retrospectively registered, https://www.thaiclinicaltrials.org/show/TCTR20221109006.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Platelet-rich fibrin as an apical barrier for MTA placement in the treatment of teeth with open apices: a pilot study

Pham,

Pham

et al. 2024

J Transl Med

View full text Add to dashboard Cite

show abstract

“…Other studies from Ricucci et al (2019) and Sabeti et al (2021) , discussed pulp histological condition after the necessary pulp procedures, while Santo et al (2021) clearly sought the impact of previous pulp inflammation on the success rate of necessary pulp therapies. The selective removal of decayed dentin, the management of deep carious lesions and the application of VPTs in pulp exposures were the topics of interest in Bjørndal et al, 2010 , Duncan et al, 2019 , Bjørndal et al, 2019 and Taha et al (2020) , while the subject covered in Croft et al, 2019 , Careddu et al, 2021 , Careddu and Duncan, 2021 and Edwards et al (2021) , also encompassed the topics mentioned above.…”

Section: Discussionmentioning

confidence: 99%