Clinical and histological characteristics of poroid neoplasms: a study of 25 cases in Taiwan

Chen, Chih Chiang; Chang, Yun Ting; Liu, Han Nan

doi:10.1111/j.1365-4632.2006.02741.x

Cited by 42 publications

(70 citation statements)

References 16 publications

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“…1 ''Hybrid'' lesions featuring a combination of 2 or more of these poroid neoplasms have been reported. 2,3 Traditionally, poroid neoplasms were considered eccrine. However, several reports documenting features of true apocrine secretion or the presence of sebaceous and/or follicular differentiation in poroma lead to the introduction of the term ''apocrine poroma.''…”

Section: Introductionmentioning

confidence: 99%

Sebaceous Differentiation in Poroid Neoplasms: Report of 11 Cases, Including a Case of Metaplastic Carcinoma Associated With Apocrine Poroma (Sarcomatoid Apocrine Porocarcinoma)

Kazakov

Kutzner

Spagnolo

et al. 2008

The American Journal of Dermatopathology

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Sebaceous differentiation in poroid neoplasms: report of 11 cases, including a case of metaplastic carcinoma associated with apocrine poroma (sarcomatoid apocrine porocarcinoma) Sebaceous differentiation in poroid neoplasms: report of 11 cases, including a case of metaplastic carcinoma associated with apocrine poroma (sarcomatoid apocrine porocarcinoma) AbstractWe describe 11 poroid neoplasms with sebaceous differentiation, including a metaplastic (sarcomatoid) carcinoma arising in association with an apocrine poroma. Six lesions had the silhouette of a classical poroma, 3 of poroid hidradenoma and 1 of dermal duct tumor. In all cases, sebaceous differentiation was identified as clustered or solitary, mature sebocytes occurring mainly at the periphery of intradermal cellular aggregations, accompanied by sebaceous ducts. In one poroma, clusters of sebocytes were seen within intradermal aggregates and intraepidermally. In 1 of the 3 poroid hidradenomas, the eosinophilic cuticle lining the cyst was crenulated in foci associated with sebocytes. In none of the cases were there signs of follicular differentiation. One poroma, in addition to sebaceous differentiation, showed decapitation secretion in some ductular structures. The single carcinoma was an ulcerated oval to spindle cell neoplasm surrounded laterally by the residuum of a poroma containing groups of sebocytes. The epithelial islands of the poroma were prominently keratinized and blended gradually with the pleomorphic cells of the metaplastic carcinoma that immunohistochemically stained focally for cytokeratins and simultaneously showed strong vimentin expression. Our study supports previous findings that sebaceous differentiation can be identified not only in classical poroma but also in the related lesions known as dermal duct tumor and poroid hidradenoma. Occurrence of metaplastic carcinoma in association with apocrine poroma is a rare event which indicates the existence of a malignant counterpart of the latter entity, which can be descriptively referred to as "sarcomatoid apocrine porocarcinoma."ORIGINAL ARTICLE We describe 11 poroid neoplasms with sebaceous differentiation, including a metaplastic (sarcomatoid) carcinoma arising in association with an apocrine poroma. Six lesions had the silhouette of a classical poroma, 3 of poroid hidradenoma and 1 of dermal duct tumor. In all cases, sebaceous differentiation was identified as clustered or solitary, mature sebocytes occurring mainly at the periphery of intradermal cellular aggregations, accompanied by sebaceous ducts. In one poroma, clusters of sebocytes were seen within intradermal aggregates and intraepidermally. In 1 of the 3 poroid hidradenomas, the eosinophilic cuticle lining the cyst was crenulated in foci associated with sebocytes. In none of the cases were there signs of follicular differentiation. One poroma, in addition to sebaceous differentiation, showed decapitation secretion in some ductular structures. The single carcinoma was an ulcerated oval to spindle cell neoplasm surrounded latera...

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Section: Introductionmentioning

confidence: 99%

Sebaceous Differentiation in Poroid Neoplasms: Report of 11 Cases, Including a Case of Metaplastic Carcinoma Associated With Apocrine Poroma (Sarcomatoid Apocrine Porocarcinoma)

Kazakov

Kutzner

Spagnolo

et al. 2008

The American Journal of Dermatopathology

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“…Battistella and co-workers 14 P + HS) among 25 tumors. 13 On the other hand, in this study, among the 384 cases we diagnosed 198 P (51.6%), 20 HS (5.2%), five D (1.3%), 56 HA (14.6%) and 105 (27.3%) composite tumors. In our study, D and P were fewer, but composite tumors were more frequently observed than in the report of Battistella et al 14 Although we cannot clearly explain such difference, we might make more strict diagnoses of each subtypes in poroid neoplasms.…”

Section: Discussionmentioning

confidence: 42%

“…In all subtypes, female cases were more frequent, even in HS that has been reported to have a male predominance. 13 Age at resection of female cases was a little higher than that of male cases. Battistella et al reported that age at resection of HS cases was higher than that of other subtypes; 5,7,14 however, in this study, that of all subtypes were almost equal.…”

Section: Discussionmentioning

confidence: 86%

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Clinicopathological analysis of 384 cases of poroid neoplasms including 98 cases of apocrine type cases

Ito

Ansai

Fukumoto

et al. 2016

The Journal of Dermatology

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We examined 384 cases of poroid neoplasms. Most cases (n = 279, 72.7%) exhibited the features of only one subtype. One hundred and ninety-eight cases (51.6%) showed only the features of poroma (P), 20 (5.2%) hidroacanthoma simplex (HS), five (1.3%) dermal duct tumor (D) and 56 (14.6%) hidradenoma (HA). Composite tumors of those four subtypes were observed in 105 cases (27.3%). In the trunk and lower extremities, lesions with the features of P were observed at higher rates than other sites. Those of HS and D were more frequently observed in the lower extremities. Those of HA were seen at higher rates in the scalp, face, neck and genitalia. Ninety-eight cases (25.5%) showed decapitation secretion and diagnosed as apocrine type lesion. Apocrine type lesions were frequently observed in the lesions on the genitalia (40.0%), scalp (31.8%) and trunk (31.1%), whereas at lower rates in those on the neck (21.4%) and lower extremities (24.0%). In apocrine type cases, the lesions were located more frequently on the scalp and trunk than non-apocrine type, whereas were less frequent on extremities. The rate of apocrine type lesions in the cases with only one subtype (19.7%) was lower than that of those with composite tumors (41.0%). In the apocrine type (43.9%), composite tumors are more frequent than in the non-apocrine type (21.7%). In D (40.8%) and HA (32.3%), apocrine type lesions were more frequently observed than other subtypes. In conclusion, it should be noted that a quarter of poroid neoplasms are composite tumors and/or show apocrine differentiation.

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“…Histologically the features of an eccrine poroma are a monomorphic proliferation of poroid and cuticular cells, with ductular differentiation and multiple points of epidermal origin [5]. Its aetiology is unknown; however, it is postulated that the following may be causative factors: solar damage, radiation exposure, trauma, and human papilloma virus [6].…”

Section: Answermentioning

confidence: 99%

An Unusual Periungual Lesion

Jayasekera

Charlton

Oliphant

2017

Skin Appendage Disord

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Clinical and histological characteristics of poroid neoplasms: a study of 25 cases in Taiwan

Cited by 42 publications

References 16 publications

Sebaceous Differentiation in Poroid Neoplasms: Report of 11 Cases, Including a Case of Metaplastic Carcinoma Associated With Apocrine Poroma (Sarcomatoid Apocrine Porocarcinoma)

Sebaceous Differentiation in Poroid Neoplasms: Report of 11 Cases, Including a Case of Metaplastic Carcinoma Associated With Apocrine Poroma (Sarcomatoid Apocrine Porocarcinoma)

Clinicopathological analysis of 384 cases of poroid neoplasms including 98 cases of apocrine type cases

An Unusual Periungual Lesion

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