Clinical and experimental use of gelatinized dacron grafts

Hara, Masauki; Love, Robert L.

doi:10.1016/0002-9610(67)90343-1

Cited by 4 publications

(1 citation statement)

References 3 publications

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“…Bascom [1], Humphries et al [14], Jordan et al [15], Wesolowski el al. [31 ] and Chvapil and Kra jicek [3] all developed collagen-coated grafts during the sixties, but their clinical applica tion has remained limited [ 13,19], In fact, it is only recently that this concept of a colla gen-coated graft has reached a commercial stage with the introduction of the Hemashield® (Mcadox Medicals, Oakland, N.J.; USA) [24] and Tascon® prostheses (Tascon Medical Technology Corp. Irvine, Calif. USA). Other coatings have been proposed for the manufacture of compound arterial prostheses.…”

Section: Introductionmentioning

confidence: 99%

Characteristics of Polyester Arterial Grafts Coated with Albumin: The Role and Importance of the Cross-Linking Chemicals

et al. 1988

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Preclotting is mandatory prior to implanting a knitted polyester arterial graft, unless the structure is made impermeable to blood by coating with a bioerodible material. Before achieving wide-spread clinical acceptance, the technique of impregnating with cross-linked albumin must be optimized in order to develop a graft that is immediately implant-able, easy to handle and suture and has improved healing characteristics. The choice of the chemical to cross-link the albumin is of paramount importance. In this study two alternative candidates have been evaluated by using a series of tests to measure the physical properties, the morphology and the cytocompatibility of albumin-coated grafts. A carbodiimide cross-linking agent appears more promising than glutaraldehyde, since it is equally effective in producing a blood impermeable prosthesis, yet presents improved biocompatibility and provokes a less intense inflammatory response from the host.

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Section: Introductionmentioning

confidence: 99%

Characteristics of Polyester Arterial Grafts Coated with Albumin: The Role and Importance of the Cross-Linking Chemicals

et al. 1988

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Long‐term behavior of bovine collagen membrane used as vascular substitute. Experimental study in rats

Chignier

Eloy

Huc³

et al. 1985

J. Biomed. Mater. Res.

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The aim of the present study was to evaluate the sequence of the immediate and the mid/long-term organization of the blood interface of a collagenous membrane used as vascular substitute in rats. The implants were prepared from calf skin type I insoluble collagen, obtained after acidic dispersion, in absence of chemical or tanning treatment. They were used to patch an aortic defect by means of microsurgical techniques. The animals were sequentially sacrificed for immediate hemocompatibility studies at 10 s, 30 s, 10 min, 3 h, and 6 h, for long-term analyses of the organization of the blood material interface at the 7th, 15th, 45th, 60th, 90th day following the surgery and each month until 14 months after aortic replacement. The superficial immediate events at the blood patch interface demonstrated erythrocytes heavily engulfed in a thin but dense fibrin mesh both at the patch and at the adjacent aortic wall surfaces. Neither adherent platelet nor platelet aggregate were detectable on the collagen patch surface. This fibrinoerythrocytic membrane covered the patch completely at 60 s and at 3 h the deposit was limited to 5-6 erythrocyte layers as confirmed by histology. It did not further develop on the 7th day. At the blood-collagen interface there progressively developed a tissue composed of active myofibroblasts, collagen bundles, and elastic fibers. After 4 months, nests of fibroendothelial cells were present, and between 6 and 14 months surface cell differentiation, although complete on the adjacent aorta was still incomplete on the bovine collagen patch, amorphous fibers, and fibroendothelial cells coexisting. Heterologous patch debris were still present 14 months after implantation and were associated with macroscopic and ultrastructural calcification, which need further investigations concerning the exact nature and mechanism of mineralization of vascular substitutes of biological nature.

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Rapid quantification of staphylococci adhered to titanium surfaces using image analyzed epifluorescence microscopy

Friedman

Draughn

et al. 1995

Journal of Microbiological Methods

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Clinical and experimental use of gelatinized dacron grafts

Cited by 4 publications

References 3 publications

Characteristics of Polyester Arterial Grafts Coated with Albumin: The Role and Importance of the Cross-Linking Chemicals

Characteristics of Polyester Arterial Grafts Coated with Albumin: The Role and Importance of the Cross-Linking Chemicals

Long‐term behavior of bovine collagen membrane used as vascular substitute. Experimental study in rats

Rapid quantification of staphylococci adhered to titanium surfaces using image analyzed epifluorescence microscopy

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