Clinical and Epidemiological Features of 46 Children &amp;lt;1 Year Old With Coronavirus Disease 2019 in Wuhan, China: A Descriptive Study

Liu, Xinghua; Tang, Jian; Xie, Rong; Li, Wei; Chen, Jianying; Guo, Yan; Zhang, Bo; Zhang, Yue; Wang, Juanjuan; Cao, Peng; Lei, Xiao; Luo, Qi; Zhang, Qiong; Li, Yunqiao

doi:10.1093/infdis/jiaa472

Cited by 29 publications

(57 citation statements)

References 10 publications

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“…Cough: Initial symptoms were fever and cough; even among neonates 30 . Cough was experienced by the majority of patients, 10‐12,14,15,19,21‐93 it was mainly dry, but was sometimes followed by productive cough in moderately severe cases 19 . There may be upper airway symptoms, such as nasal congestion, rhinitis, and sore throat 19 .…”

Section: Resultsmentioning

confidence: 99%

“…Fever: One of the commonest early symptoms is fever, 11,14,15,19‐22,25‐36,38‐58,61‐65,67,68,70‐106 occasionally low grade. In Zhejiang province, fever clinics that exclusively accept for admission patients suspected of being positive for SARS‐CoV‐2 were set up 27 …”

Section: Resultsmentioning

confidence: 99%

“…Gastrointestinal symptoms: It is currently reported that SARS‐CoV‐2, despite being predominantly a respiratory virus, causes gastrointestinal symptoms in approximately 10% of infected children, 134,167 including abdominal pain, diarrhea, and vomiting 11,14,15,19,20,22,26,28,31,40,41,52,53,57,59,62,65,67,70‐73,77,81,83,84,86‐93,100,104,106‐108,114,116 …”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

“…Laboratory results: Complete blood counts may be normal, 11,14‐16,19,22,26,29,32,39,40,44,48‐50,54,61,79,93,102,165,168 or show either decreased 14,16,19,25,26,29,31,39,40,44,49,55,61,70,93,100,108 or elevated white blood cell counts 11,14,20,22,26,44,47,50,54,60,61,93,99 . Lymphocyte counts may be increased, 15,19,24,26,29,44,60,78,79,82,84,93,96,103,169 or decreased 14,19,22,23,25‐28,31,34,39,44,49,55,70,79,82,84,88,99,100,103,113,116 . Increased C‐reactive protein (CRP), 15,19,22,25,26,28,29,31,40,41,44,47,49,50,56,73,74,77,83,84,88,93,101,103,104 procalcitonin (PCT) 15,22,26,31,44,49,50,56,73,77,84,88,93,99 and lactate dehydrogenase 14,15,22,25,47,81,83,84,93 have been reported.…”

Section: Resultsmentioning

confidence: 99%

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Coronavirus global pandemic: An overview of current findings among pediatric patients

Perikleous

Tsalkidis

Bush

et al. 2020

Pediatric Pulmonology

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Background The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) epidemic has been emerged as a cardinal public health problem. Children have their own specific clinical features; notably, they seem to be escaping the severe respiratory adverse effects. The international scientific community is rapidly carrying out studies, driving to the need to reassess knowledge of the disease and therapeutic strategies. Aim To assess the characteristics of COVID‐19 infected children worldwide of all ages, from neonates to children and adolescents, and how they differ from their adult counterparts. Search Strategy An electronic search in PubMed was conducted, using combinations of the following keywords: coronavirus, SARS‐CoV‐2, COVID‐19, children. The search included all types of articles written in English between January 1, 2019 until August 15, 2020. Results The search identified 266 relevant articles. Children were mainly within family clusters of cases and have relatively milder clinical presentation compared with adults; children were reported to have better outcomes with a significantly lower mortality rate. Cough and fever were the most common symptoms while pneumonia was the cardinal respiratory manifestation of infected children. Laboratory results and thoracic imaging give varying results. Conclusions Children were mainly family cluster cases and usually presented with a mild infection, although cases presented with the multisystem inflammatory syndrome are becoming more apparent. Studies determining why the manifestations of SARS‐CoV‐2 infection are so variable may help to gain a better understanding of the disease and accelerate the development of vaccines and therapies.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

Coronavirus global pandemic: An overview of current findings among pediatric patients

Perikleous

Tsalkidis

Bush

et al. 2020

Pediatric Pulmonology

View full text Add to dashboard Cite

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Clinical Characteristics and Disease Severity Among Infants With SARS-CoV-2 Infection in Montreal, Quebec, Canada

et al. 2020

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Twelve Months with COVID-19: What Gastroenterologists Need to Know

et al. 2021

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Corona virus disease-19 (COVID-19) is the latest global pandemic. COVID-19 is mainly transmitted through respiratory droplets and, apart from respiratory symptoms, patients often present with gastrointestinal symptoms and liver involvement. Given the high percentage of COVID-19 patients that present with gastrointestinal symptoms (GIS), in this review, we report a practical up-to-date reference for the physician in their clinical practice with patients affected by chronic gastrointestinal (GI) diseases (inflammatory bowel disease, coeliac disease, chronic liver disease) at the time of COVID-19. First, we summarised data on the origin and pathogenetic mechanism of SARS-CoV-2. Then, we performed a literature search up to December 2020 examining clinical manifestations of GI involvement. Next, we illustrated and summarised the most recent guidelines on how to adhere to GI procedures (endoscopy, liver biopsy, faecal transplantation), maintaining social distance and how to deal with immunosuppressive treatment. Finally, we focussed on some special conditions such as faecal–oral transmission and gut microbiota. The rapid accumulation of information relating to this condition makes it particularly essential to revise the literature to take account of the most recent publications for medical consultation and patient care. Supplementary Information The online version contains supplementary material available at 10.1007/s10620-021-07158-0.

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Clinical and Epidemiological Features of 46 Children <1 Year Old With Coronavirus Disease 2019 in Wuhan, China: A Descriptive Study

Cited by 29 publications

References 10 publications

Coronavirus global pandemic: An overview of current findings among pediatric patients

Coronavirus global pandemic: An overview of current findings among pediatric patients

Clinical Characteristics and Disease Severity Among Infants With SARS-CoV-2 Infection in Montreal, Quebec, Canada

Twelve Months with COVID-19: What Gastroenterologists Need to Know

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