Clinical and economic evaluation of the use of enteral nutrition products

Abstract

Introduction. The development and study of new enteral nutrition (EN) formulas is a major challenge to modern practical medicine. The creation of enteral nutrition products, which in addition to their intrinsic nutritional properties have detoxifying properties, will contribute to enhanced clinical efficacy and more active recovery of patients.Aim. To conduct a comparative pharmaco-economic analysis of the effectiveness of using new domestic products for enteral nutrition produced by LEOVIT Nutrio (Russia), which have detoxifying activity, and products from other manufacturers.Materials and methods. The studies were carried out using standard cost-effectiveness analysis techniques. A comparative analysis of following products:Nutrien Standard (JSC Infaprim, Russia), Supportan drink (FreseniusKabi, Germany), Nutridrink compact protein (Nutricia, Holland) and Peptamen (Nestle, Switzerland), Detoxifying Protein Cocktail, Restoring Protein Cocktail and Detoxifying Drink (LEOVIT Nutrio LLC, Russia).Results and discussion. Calculations for all analyzed economic parameters showed the advantages of using new domestic products for enteral nutrition. It was found that the total direct costs for enteral nutrition in the group of cancer patients who additionally took a detoxification cocktail were the smallest and amounted to 3332.0 rub, the increase in blood protein concentration over 14 days of therapy was 11.1 g/l, and for albumin over the indicated period is 6.7 g/l. Compared to products from other manufacturers, the lowest cost in relation to the achieved effect (CER) was observed when using a restorative cocktail – 305.69 rub. for protein and 512.62 rub. by albumin. The total direct costs for enteral nutrition in the group of patients who took the Detoxification Drink in comparison with other products on the Russian market were also the lowest and amounted to 840.00 rubles.Conclusions. The authors concluded that there are significant economic advantages of using the new domestic enteral nutrition LEOVIT compared to other products and consider them as the product of choice when providing enteral protein nutrition to patients with various diseases accompanied by intoxication of the organism.