Clinical and Diagnostic Implications of Lifetime Attention-Deficit/Hyperactivity Disorder Comorbidity in Adults with Bipolar Disorder: Data from the First 1000 STEP-BD Participants

Nierenberg, Andrew A.; Miyahara, Sachiko; Spencer, Tom; Wisniewski, Stephen R.; Otto, Michael W.; Simon, Naomi M.; Pollack, Mark H.; Ostacher, Michael J.; Liu, Yan; Siegel, Rebecca S.; Sachs, Gary S.

doi:10.1016/j.biopsych.2005.01.036

Cited by 241 publications

(231 citation statements)

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“…[32] Dikkat eksikliği ve hiperaktivite bozukluğu bipolar bozukluk tanısı almış hastaların %10'unda görülmektedir. [33] BDT her iki bozukluğa sahip kişiler-de kullanılan psikososyal müdahalelerden biri olmakla birlikte bu konuda yapılan bir çalışma bulunmamaktadır. Benzer bir durum yeme bozuklukları için de geçerlidir.…”

Section: Bipolar Bozuklukta Uygulanan Bdt'nin İçeriğiunclassified

Cognitive Behavioral Therapy in Bipolar Disorder

Maçkalı¹,

Tosun²

2011

Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychia

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ÖZETBipolar bozukluk, erken başlangıçlı ve kronik seyri nedeniyle kişinin mesleki, sosyal ve yakın ilişki alanlarında bozulmalara yol açan, hastalığa ve hastalığın tedavisine uyum yapmayı öğrenmenin kritik öneme sahip olduğu bir bozukluktur. Bu nedenle bipolar bozukluğun tedavisinde, biyolojik müdahalelerin yanında psikososyal müdahalelerin de gerekli olduğu görüşü giderek yaygınlık kazanmaktadır. Bunun bir sonucu olarak, bipolar bozuklukta hangi psikososyal müdahalelerin etkili olduğunun belirlenmesi konusu önem taşı-maktadır. Bu yazıda bipolar bozuklukta ilaç tedavisine ek olarak uygulanan bilişsel davranışçı terapi uygulamaları ele alınıp, bu uygulamaların bipolar bozukluktaki etkinliğini inceleyen araştırmalar değerlendirilmiştir. Anahtar Sözcükler: bipolar bozukluk, bilişsel davranışçı terapi, tedavi ABSTRACT Bipolar disorder is an early-onset, chronic disorder. It impairs occupational, social, and family functioning, which makes learning to adapt living with the disorder and its treatment critically important. Therefore, it has now become common knowledge that psychosocial interventions are also necessary in the treatment of bipolar disorder adjunctive to pharmacotherapy. Thus, whichever psychosocial interventions are more effective in bipolar disorder is a crucial research question. In this article, cognitive-behavioral therapy, which is applied adjunctive to pharmacotherapy, will be addressed and the findings of research about the effectiveness of these applications will be reviewed.

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Section: Bipolar Bozuklukta Uygulanan Bdt'nin İçeriğiunclassified

Cognitive Behavioral Therapy in Bipolar Disorder

Maçkalı¹,

Tosun²

2011

Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychia

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“…Chez l'adulte, plusieurs études ont montré que les deux troubles coexistaient en moyenne dans 20 % des cas [12,16,24]. Ainsi, la prévalence de l'association TDAH-TB dans la population générale adulte est estimée entre 0,2 % et 0,4 %.…”

Section: Comorbidité Tb Et Tdah : Une Situation Clinique Complexeunclassified

Trouble bipolaire et trouble déficit d’attention avec hyperactivité

Besnier

2009

Annales Médico-psychologiques, revue psychiatrique

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This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. cependant, certains travaux suggèrent que le TB serait une perturbation essentielle de la réponse émotionnelle, tandis qu'une perturbation du contrôle cognitif serait fondamentale dans la genèse des symptômes du TDAH. La comorbidité de ces deux troubles, fréquente, montre un tableau clinique sévère, au schéma thérapeutique complexe. En association avec les thymorégulateurs, la prescription de psychostimulants peut contribuer à améliorer la symptomatologie et le fonctionnement intercritique. AbstractThe distinction between bipolar disorder (BD) and Attention Deficit Hyperactivity

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“…Further, these ADHD and BD subjects also had higher rates of several anxiety disorders and alcohol and substance abuse and dependence. 29 STEP-BD findings on the comorbidity with alcohol disorders were modest. Examining the first 1000 STEP-BD participants, recovery in BD was less common in those with either current or previous SUDs.…”

Section: Comorbidity With Other Psychiatric Disordersmentioning

confidence: 99%

Advancing Bipolar Disorder: Key Lessons from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)

2010

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W La Revue canadienne de psychiatrie, vol 55, no 3, mars 2010 136Objective: To review the overall clinical research findings from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD), the world's largest study of BD.Methods: STEP-BD was conducted from 1998 to 2005, enrolling participants (n = 4361) across 22 clinical sites in the United States. Each individual was followed for up to 2 years in naturalistic practice with blinded research assessments, while subgroups participated in randomized controlled trials (RCTs) for bipolar depression. The naturalistic database was used to examine the course of BD, comorbidity with other psychiatric disorders, and suicidality. Relevant studies in English, published from January 1, 1994, to May 31, 2009, were identified using computerized searches of electronic databases (PubMed, PsycINFO, and Cochrane Register of Clinical Trials), inspection of bibliographies, and review of other major reports. Results:One large RCT involving the addition of either paroxetine or bupropion to mood stabilizers in acute depression found neither more effective than placebo in achieving sustained recovery (8 weeks of euthymia). A second large RCT found intensive psychosocial interventions superior to a brief psychosocial intervention as an adjunct to medication in acute depression. A third small RCT found minimal effects of lamotrigine, risperidone, or inositol in refractory depression. Recovery was difficult to achieve, with subsyndromal symptoms or full relapse very common. Anxiety disorders and smoking in particular were treatable conditions that adversely affected the course of BD.Conclusions: STEP-BD yielded numerous clinical and systems observations that provide fresh direction for research and treatment of BD, including setting new benchmarks for outcome and demonstrating the viability of large BD networks.Can J Psychiatry. 2010;55(3):136-143. Highlights· STEP-BD was the largest BD research program ever conducted, and included data from 3 major RCTs and findings from many observational studies. · Few treatments were successful in bipolar depression, with psychosocial interventions combined with mood stabilizers the most positive. · Comorbidity of BD with substance abuse and smoking were common and adversely affected clinical outcome, while comorbidity with adult attention-deficit hyperactivity disorder was modest.

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Clinical and Diagnostic Implications of Lifetime Attention-Deficit/Hyperactivity Disorder Comorbidity in Adults with Bipolar Disorder: Data from the First 1000 STEP-BD Participants

Cited by 241 publications

References 28 publications

Cognitive Behavioral Therapy in Bipolar Disorder

Cognitive Behavioral Therapy in Bipolar Disorder

Trouble bipolaire et trouble déficit d’attention avec hyperactivité

Advancing Bipolar Disorder: Key Lessons from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)

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