Clinical and bacteriological profile and outcome of sepsis in dermatology ward in tertiary care center in New Delhi

Abstract

Sepsis occurred in 40 (4.65%) inpatients in dermatology ward. The frequency of sepsis was highest in TEN (90%), followed by drug-induced maculopapular rash (20.0%), erythroderma (17.5%), and vesicobullous diseases (8.5%). MRSA, acinetobacter, pseudomonas, MSSA, and Klebsiella were important etiological agents involved in sepsis in dermatology in-patients.

A study of the prevalence of methicillin-resistant Staphylococcus aureus in dermatology inpatients

“…This is similar to the other Indian studies by Asati et al ., Sharma et al ., and Malhotra et al . [7810] A total of 36.1% of the cases in the present study had duration of illness less than two weeks duration, which chiefly comprised the primary pyodermas and eczemas, while long duration of illness was seen in the vesiculobullous group. Many studies have shown that the duration of illness was found to correlate with the risk of MRSA infection, especially in cases of autoimmune vesiculobullous disorders.…”

“…[9] Male preponderance has been found in other Indian studies also. [710] However, in the study by Asati et al .,[8] there was a female preponderance.…”

“…In the study by Sharma et al ., and in the study by Asati et al ., bacterial infections in the wards accounted for 6.6% and 4.65%, respectively. [78]…”

“…[78] It is a well-known fact that DM predisposes to sepsis, especially in the chronic-debilitated patient.…”

“…[78101112] Seven cases of autoimmune vesiculobullous disorders, mainly pemphigus and pemphigoid were positive for MRSA culture, even though this was not statistically significant ( P = 0.54). In the present study, 10 patients (62.5%) with MRSA infection were on prolonged antibiotic therapy and immunosuppressive therapy, mainly oral corticosteroids, even though this was not statistically significant ( P = 0.16).…”