Clinical and Angiographic Predictors and Prognostic Value of Failed Thrombus Aspiration in Primary Percutaneous Coronary Intervention

Abstract

The presence of marked proximal tortuosity of the infarct-related artery, a calcified lesion, and a bifurcation lesion are independent predictors of failure of thrombus aspiration. We found that unsuccessful TA did not affect 1-year mortality.

Vaporizing Thrombus With Excimer Laser Before Coronary Stenting Improves Myocardial Reperfusion in Acute Coronary Syndrome

“…In previous studies, failure to reach or cross the culprit lesions occurred in approximately 4-11% of patients, and thrombotic material could not be collected in approximately 25% of patients, although the aspiration catheter was successfully delivered. 6,26,31, 32 In the present study, the laser catheters crossed the lesion in 96.2% of cases, whereas the aspiration catheters crossed the lesion in 82.6% of cases. Furthermore, the laser catheter crossed all lesions in the patients in whom the aspiration catheter did not cross.…”

Aspiration Thrombectomy for Treatment of ST-segment Elevation Myocardial Infarction: a Meta-analysis of 26 Randomized Trials in 11 943 Patients

“…[27][28][29][30] Even in the case of effective thrombectomy, other determinants of prognosis including ischemic time, extent of the area at risk, presence of collateral flow before the procedure, and quality of reperfusion at the end of the procedure, as well as stent type, need to be considered. [31][32][33] The interplay between these factors may importantly diminish the impact of AT on overall mortality in unselected STEMI patients.…”

Possible Benefits of Catheters With Lateral Holes in Coronary Thrombus Aspiration: A Computational Study for Different Clot Viscosities and Vacuum Pressures

“…In particular, possible benefits of using tips with lateral holes in addition to a central lumen were assessed. Although a number of trial studies have been done considering the pros and cons of thrombectomy devices (1,5,20), a specific study investigating the role of tip geometry in aspiration of clots with different properties and at different applied pressures is lacking. The two-phase flow strategy applied to the study of clot aspiration (i.e., considering both blood and blood clot as fluids) was originally suggested by Pennati et al (10).…”