Clinical and Anatomical Forms of Congenital Cleft Lip and Palate in the Region With Ecotoxicants

Abstract

Subject: the study of the features of clinical and anatomical forms of congenital cleft lip and palate in the region with the petrochemical industry.
 Objectives ― determination of the clinical-anatomical forms of congenital cleft lip and palate, the identification of the frequency of severe forms in the region with the petrochemical industry and in the region without industrial eco-toxicants.
 Methods. We have studied medical documentation in the Department of Maxillofacial Surgery of the Republican Children's Clinical Hospital for the period from January 1, 1985 to December 31, 2018 to study the structure of the clinical and anatomical forms of congenital clefts of the lips and palate in children living in the Republic of Bashkortostan. During the analyzed period, 3463 children from birth to 16 years with congenital cleft lip and palate underwent treatment and dispensary observation.
 Results. Our data suggest that in the area with petrochemical ecotoxicants, the percentage of severe forms of congenital cleft lip and palate is higher (77.5%) than in an area without petrochemical ecotoxicants (68.7%).
 Conclusions. Thus, environmental pollution by petrochemical ecotoxicants leads to an increase in the number of children with congenital cleft lip and palate. There is a relationship between the level of air pollution by gross emissions from petrochemical enterprises and the severity of the clinical-anatomical forms of congenital cleft lip and palate in children living in an industrial area. It is important and important in the prenatal prevention of congenital clefts of the lip and palate.