Clinical Analysis of Pediatric Glaucoma in Central China

Liu, Qian; Liu, Changgeng; Li, Haijun; Yang, Xiaoyuan; Dong, Yangzeng; Feng, Xiaomei; Cheng, Wenjun

doi:10.3389/fmed.2022.874369

Cited by 4 publications

(2 citation statements)

References 39 publications

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“…Также был проведен статистический анализ, позволивший математически выявить случаи накопления и локально высоких значений распространенности того или иного наследственного заболевания в отдельных популяциях и/или этнических группах. С учетом анализа накопления заболеваний по популяциям разных регионов страны, на основании рассчитанных показателей критических значений по F-распределению (уровень значимости α < 0,01) установлено накопление аутосомнорецессивной ПВГ (3,14) у русских из Кировской области. О более высокой распространенности ПВГ в Кировской области уже сообщалось ранее, когда были приведена цифра 8,03 на 100 тыс.…”

Section: западная европаunclassified

Genetic Epidemiology of Primary Congenital Glaucoma in the World. Part II

Oganezova,

Kadyshev,

Egorov

2024

Oftalʹmologiâ

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This publication continues a review published in December 2023 about the genetic epidemiology and genotype-phenotype correlations in primary congenital glaucoma (PCG) worldwide, and presents data from East and South Asia, Western Europe and Russia. Analysis of the incidence of PCG data in these regions shows that the rates for Western Europe, the European part of Russia and East Asia are comparable and average 1:10,000–18,000 newborns and higher in ethnically mixed groups. On the territory of South Asia, the minimum number of children with PCG was recorded in Nepal, and the maximum in India. The majority of researchers talk about the predominance of bilateral process in 62 to 99 % cases. As a rule, there is a slight predominance of boys among patients with PCG; authors from India and France report approximately the same number of boys and girls, and German scientists have found a higher prevalence of PCG among girls. If we talk about the phenotype of the disease, almost all researchers note a more severe course in subgroups with the presence of CYP1B1 mutations than in patients who do not have a mutation in this gene. As for the genetic causes of PCG, the most common are mutations in the CYP1B1 gene, accounting for up to a third of cases in India, Pakistan, Western Europe and the European part of Russia. In East Asian patients, mutations in the CYP1B1 gene are most likely not the main ones in the pathogenesis of PCG, because are found much less frequently and often only in one allele. Chinese scientists say that it is necessary to pay attention to mutations TEK and ZC2HC1C, VPS13D, PGF.

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Section: западная европаunclassified

Genetic Epidemiology of Primary Congenital Glaucoma in the World. Part II

Oganezova,

Kadyshev,

Egorov

2024

Oftalʹmologiâ

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“…Hospital-or institution-based rehabilitation therapy not only results in substantial economic costs but also requires signi cant human and time resources from families [9,10]. Owing to disparities in regional development in China, most remote areas lack the essential medical infrastructure to cater to the basic rehabilitation needs of CP patients [11,12]. Thus, identifying a reliable and convenient approach to promote the use of home-based rehabilitation training for families affected by CP is crucial.…”

Section: Introductionmentioning

confidence: 99%

Quality of Cerebral Palsy-Related Videos on Chinese Social Media Platforms

He,

Tang,

Jin

et al. 2024

Preprint

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Background A significant research gap exists in evaluating the prevalence and quality of Chinese videos depicting CP on domestic social media platforms. In contrast to studies that focus on online video content concerning CP on YouTube, CP videos on YouTube are largely inaccessible to average citizens in mainland China. This disparity underscores the need for further investigation into the availability and nature of CP videos specifically on Chinese social media platforms. Methods The present cross-sectional study examined 344 videos about CP from popular Chinese social media platforms, including TikTok, Kwai, Weibo, Bilibili, and RED. The analysis of these videos involved a detailed assessment of their sources, content, and characteristics. Additionally, quantitative scoring tools such as Journal of the American Medical Association (JAMA) Benchmarks, Global Quality Score (GQS), and DISCERN were utilized to evaluate video quality. Furthermore, the potential relationship between video quality and various attributes such as duration, number of likes, and comments was explored and their impact on the quality of information presented in the videos was analyzed. Results The average duration of the 344 videos was 92.12 seconds (SD 105.69). CP rehabilitation training videos comprised 45.64% of the total, followed by expert-contributed videos at 40.70%. Mean scores for JAMA, GQS, and DISCERN were 1.62 (SD 0.60), 2.05 (SD 0.99), and 1.26 (SD 1.26) respectively. RED had the lowest average scores. Videos focusing on disease knowledge scored highest on JAMA and GQS scales. Experts achieved significantly higher GQS and DISCERN scores compared to health-related institutions and amateurs. Spearman correlation analysis revealed a strong positive correlation between likes and comments (r = 0.87, P < .001). Conclusion Enhancing the management of medical content is crucial to address the compromised reliability of Chinese online short videos providing information to families of CP patients. Improving content professionalism and accuracy ensures users access genuinely valuable information.

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Clinical analysis of secondary glaucoma in Central China

Liu

Cheng

et al. 2023

Sci Rep

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To describe the epidemiology, clinical and social characteristics, management, and outcomes of patients with secondary glaucoma in Central China, a total of 1,129 cases (1,158 eyes) among 710 males (62.89%) and 419 females (37.11%) were analyzed. The mean age was 53.75 ± 17.11 years. The New Rural Cooperative Medical System (NCMS) played the most important role in reimbursement (60.32%) for secondary glaucoma-related medical expenses. The predominant occupation was “farmer” (53.41%). Neovascularization and trauma were the leading causes of secondary glaucoma. Cases of trauma-induced glaucoma decreased substantially during the coronavirus disease 2019 (COVID-19) pandemic. An education level of senior high school or above was uncommon. Ahmed glaucoma valve implantation was the most commonly performed surgery. At the final follow-up, the overall intraocular pressure (IOP) in patients with vascular disease- and trauma-related secondary glaucoma was 19.53 ± 10.20 mmHg, 20.26 ± 11.75 mmHg, and 16.90 ± 6.72 mmHg, while the mean visual acuity (VA) was 0.33 ± 0.32, 0.34 ± 0.36, and 0.43 ± 0.36. In 814 (70.29%) eyes, the VA was < 0.01. Effective preventive measures for at-risk populations, increased NCMS coverage and the promotion of higher education are necessary. These findings will help ophthalmologists detect secondary glaucoma early and manage it in a timely manner.

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Clinical Analysis of Pediatric Glaucoma in Central China

Cited by 4 publications

References 39 publications

Genetic Epidemiology of Primary Congenital Glaucoma in the World. Part II

Genetic Epidemiology of Primary Congenital Glaucoma in the World. Part II

Quality of Cerebral Palsy-Related Videos on Chinese Social Media Platforms

Clinical analysis of secondary glaucoma in Central China

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