Clinic Value of Two‐Dimensional Speckle Tracking Combined with Adenosine Stress Echocardiography for Assessment of Myocardial Viability

Ran, Hong; Zhang, Pingyang; Fang, Lingling; Ma, Xiuli; Wu, Wei; Feng, Wang-fei

doi:10.1111/j.1540-8175.2012.01690.x

Cited by 23 publications

(21 citation statements)

References 23 publications

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“…Coronary hyperemia induced by ATP infusion has been reported to result in hyperkinetic wall motion in normal myocardium. 20 The increase in C-strain under ATP-stress in non-ischemic and control segments, as indicated in Figure 4, correlates with the physiological status under ATP-stress conditions. or infarction (7±12% and 5±10%, respectively; P<0.001).…”

Section: Comparison Of C-strain Under Atp-stress and At-rest Conditionsmentioning

confidence: 99%

Stress/Rest Circumferential Strain in Non-Ischemia, Ischemia, and Infarction

Nagao

Kido

Kurata

et al. 2013

Circ J

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Background: Adenosine triphosphate (ATP) induces relative hypoperfusion in significantly stenotic coronary arteries, but its effect on myocardial strain has not been used clinically for the detection of ischemia. The purpose of this study was to quantify ATP-stress-induced contractile impairment as altered myocardial strain in coronary artery disease (CAD) using tagged magnetic resonance (MR) and to evaluate its diagnostic capability in comparison with ATP-stress myocardial perfusion-MR. Methods and Results:Tagged MR and perfusion-MR under ATP-stress and rest conditions and late gadolinium enhancement (LGE) MR imaging were performed in 22 patients with suspected CAD. The peak absolute value of the circumferential strain (C-strain) was measured in 12 segments. Myocardial segments were categorized as nonischemic (n=201), ischemic (n=42), or infarcted (n=21) according to the perfusion-MR and LGE MR imaging results. The absolute C-strain was significantly greater under ATP-stress (19±13%) (mean ± SD) than under at-rest (15±11%, P<0.001) conditions in non-ischemic segments. Conversely, the absolute C-strain was significantly lower under ATP-stress (10±13%) than under at-rest (16±6%, P<0.01) conditions in ischemic segments. Optimal cutoff values for stress C-strain (-17.5%) could successfully differentiate segments with ischemia or infarction from non-ischemic ones with a sensitivity of 86%, a specificity of 65%, and an area under the curve of 0.79. Conclusions:C-strain analysis using tagged MR could detect ATP-stress-induced contractile impairment in ischemic myocardium. (Circ J 2013; 77: 1235 -1241

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Section: Comparison Of C-strain Under Atp-stress and At-rest Conditionsmentioning

confidence: 99%

Stress/Rest Circumferential Strain in Non-Ischemia, Ischemia, and Infarction

Nagao

Kido

Kurata

et al. 2013

Circ J

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“…Myocardial viability was determined in all myocardial segments using radionuclide imaging of myocardial perfusion and myocardial metabolism. An increase in strain rate identified viable myocardial segments, while non--viable segments exhibited no increase in strain rate [19].…”

Section: Discussionmentioning

confidence: 99%

“…Ran et al [19] used adenosine as a different method of pharmacological stress testing during echocardiographic examination. Myocardial strain was calculated by the method of speckle tracking echocardiography.…”

Section: Discussionmentioning

confidence: 99%

Regional myocardial contractile reserve assessed by strain echocardiography and the response to cardiac resynchronization therapy

et al. 2014

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non-responders (2.14 ± 2.9 vs. -0.94 ± 1.74, p = 0.042). Patients with increased deformation in the LV lead area during dobutamine stimulation were more likely to be responders to CRT compared to patients without increased deformation in this area (81% vs. 20%, p = 0.0002). They exhibited significant increase in LVEF (8.8% ± 10.3% vs. 0.3% ± 6.4%, p = 0.01). LV electrode localization in viable myocardium was a good predictor of response to CRT (AUC 0.852, p < 0.0001). Conclusions: Regional contractile reserve assessed by strain rate echocardiography during dobutamine infusion predicts the response to CRT. (Cardiol J 2014; 21, 5: 524-531)

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“…usually at rest, there is no significant difference between the viable and nonviable myocardium strain. with adenosine stress, viable segments increase their longitudinal strain in contrast to non-viable ones which remain unchanged 15 .…”

Section: Stress Echocardiographymentioning

confidence: 99%

“…2D speckle tracking stress echocardiography; Ran et al (2012), in a recent trial assessed patients who had sustained a MI and eF of 40% (±6%) and showed that using adenosine stress, radial myocardial strain more than 9.5% had a sensitivity of 83.9% and a specificity of 81.4% for detecting viable myocardium, whereas a change of longitudinal strain more than 14.6% displayed a sensitivity of 86.7% and a specificity of 90.2%. peak-systolic circumferential strain however, had little effect on viability assessment 15 .…”

Section: Doppler Cfr Echocardiographymentioning

confidence: 99%

Assessment of Myocardial Viability: A Review of Current Non Invasive Imaging Techniques

Talib¹

2015

ICFJ

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Coronary artery disease (CAD) is the most prevalent and single most common cause of morbidity and mortality1 with the resulting left ventricular dysfunction (LVD) an important complication2. Worldwide, CAD accounts for 5.7 million new cases per year, of these 1.3 million in Europe alone3. In addition, it imposes a substantial share of health service resources and expenses, an impaired quality of life, disability and high social cost3,4. Furthermore, LVD itself has been shown to be a powerful determinant of survival2, 5.

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Clinic Value of Two‐Dimensional Speckle Tracking Combined with Adenosine Stress Echocardiography for Assessment of Myocardial Viability

Abstract: 2D STI combined with adenosine stress echocardiography could provide a new and reliable method to identify myocardium viability.

Cited by 23 publications

References 23 publications

Stress/Rest Circumferential Strain in Non-Ischemia, Ischemia, and Infarction

Stress/Rest Circumferential Strain in Non-Ischemia, Ischemia, and Infarction

Regional myocardial contractile reserve assessed by strain echocardiography and the response to cardiac resynchronization therapy

Assessment of Myocardial Viability: A Review of Current Non Invasive Imaging Techniques

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