Climate change and the rising incidence of vector-borne diseases globally

Abrupt Increase in Detection of Locally Acquired West-Nile-Virus-Lineage-2-Mediated Neuroinvasive Disease in a Previously Non-Endemic Area of Southern Italy (2023)

“…In particular, temperature and precipitation played a crucial role in WNV spreading in horses and humans [ 5 ]. In fact, due to climate changes, diseases transmitted by Aedes, Culex, and Anopheles mosquitoes will significantly impact human health, and, according to the World Health Organization, in the next decades, malnutrition, heat stress, and vector-borne diseases will cause an additional 250,000 deaths per year [ 22 , 23 ].…”

How climate change is changing vaccination planning

“…Included on their short list of candidates are vaccines for dengue and Shigella. Rising temperatures and precipitation levels have allowed for the spread of bacteria like Shigella and mosquitoes which carry viruses such as dengue 34. In Bangladesh, for example, longer monsoon seasons and rising temperatures mean mosquitoes proliferate.…”

In Silico Drug Repurposing Uncovered the Antiviral Potential of the Antiparasitic Drug Oxibendazole Against the Chikungunya Virus

“…The effects of OBZ and its analogs ABZ, MBZ, and FBZ on Vero cell viability were measured by MTT assay. Vero cells (2 × 10 4 cells/well) were treated with different concentrations (10,50,125,250, and 500 μM) of the compounds for 72 h at 37 °C and 5% CO 2 atmosphere. CQ (62.5, 125, 250, 500, and 1000 μM) were also evaluated.…”

“…8 In 2023, many Latin American countries experienced a remarkable increase in CHIKV cases and deaths, which led the World Health Organization to issue an alert for enhancing surveillance and control strategies in the region. 9 In addition, climate changes along with globalization significantly affect mosquitoes distribution 10 and approximately 50% of the global population will likely be at risk for arbovirus transmission in the next decades. 11 Usually, Chikungunya fever is self-limited and characterized by fever, rash, arthralgia or polyarthralgia, myalgia, headache, and edema.…”