Clear cell renal carcinoma masquerading as thyroid enlargement

Gault, Edward W.; Leung, Tze-ming.; Thomas, D.

doi:10.1002/path.1711130103

Cited by 43 publications

(22 citation statements)

References 14 publications

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“…About a half of patients received total thyroidect- omies in the published series, and in others limited resections had been performed, without indices of worse outcomes in latter (2,4,(13)(14)(15)(16). Bilateral involvement of the gland and multiple metastases are common (2); however, they can be detected preoperatively or at the time of the surgery in most cases.…”

Section: Discussionmentioning

confidence: 96%

Renal Cell Carcinoma Metastases to the Thyroid Gland—8 Cases Reported

Iesalnieks

Trupka

Raab³

et al. 2007

Thyroid

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Section: Discussionmentioning

confidence: 96%

Renal Cell Carcinoma Metastases to the Thyroid Gland—8 Cases Reported

Iesalnieks

Trupka

Raab³

et al. 2007

Thyroid

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“…On the other hand, there have been several reports on metastasis of renal cell carcinoma to the thyroid, which appeared prior to the primary tumor being detected. 13,14 In most such cases, the thyroid tumor has been resected as a primary thyroid tumor and postoperative histological examinations have revealed metastases of the renal clear cell carcinoma which could finally be detected by subsequent abdominal examinations. Therefore, it is of primary importance that the possibility of metastasis from renal cell carcinoma should be taken into account, especially when histological examinations reveal a clear cell thyroid lesion.…”

Section: Discussionmentioning

confidence: 99%

Solitary Thyroid Metastasis of Renal Clear Cell Carcinoma: Report of a Case

Seki¹,

Ueda²,

Shibata³

et al. 2001

Surgery Today

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A case of solitary thyroid metastasis of renal clear cell carcinoma is described. The patient was a 77-year-old Japanese woman, who was referred to our department after a thyroid tumor was identified in May 1999. She had a history of renal clear cell carcinoma of the left kidney, which had been partially resected 3 years previously. Ultrasound sonography demonstrated that a well-demarcated hypoechoic mass containing high-echo spots representing small calcifications, which measured 45 x 34 x 31 mm in size, occupied the left lobe. Computed tomography revealed a low-density mass containing small calcifications. The results of preoperative fine-needle aspiration cytology strongly suggested a clear cell carcinoma metastasizing to the thyroid. A left hemithyroidectomy was performed on July 27, 1999. A histological examination revealed that the neoplasm was composed of tumor cells with abundant clear cytoplasm and round nuclei. The histological characteristics of this thyroid tumor were virtually identical to the renal cell carcinoma resected 3 years previously. Thyroglobulin stained negatively in the clear cells of the resected thyroid tumor in an immunohistochemical analysis. Clinically, the thyroid gland is a rare site of tumor metastasis; however, we should also consider the possibility of metastasis in the case of thyroid tumor patients with a history of renal cell carcinoma.

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“…[19][20][21][22] In our study, long dissent preterminal events, and the average survival from diagnosis to death is 2 months. 24 The clinical course ease free intervals were present not only in renal cell carcinoma patients, but also in some patients with of the patients with melanoma and carcinomas of the lung and the esophagus was more rapid and reached breast and uterine adenocarcinoma.…”

Section: Course Of Disease and Treatmentmentioning

confidence: 99%