Clear Cell Hidradenoma of the Ear Lobule: An Unusual Site of Presentation

Abstract

The origin of hidradenoma was from the eccrine sweat glands, generally found in the head, face, and upper extremity regions. This lesion has not been reported to be large enough to present in the ear lobule. Hence, its description in the otolaryngology literature is extremely rare. The rarity of this neoplasm and failure to identify its morphologic features may lead to misdiagnosis. We present a benign clear cell hidradenoma of the right ear lobule in a 45-year adult male. We encountered a tumour measuring 4 cm in diameter. Mass shows ulcerated surface, bleeds on touch and remained a diagnostic dilemma till an excision biopsy was carried out and a histopathological report confirmed that it was a hidradenoma of clear cell variant. The aim of presenting this case report was interesting in the fact that it has added clear cell hidradenoma in the final diagnosis, in an uncommon site of presentation.

Eccrine hidradenoma of the breast: distinct pathological lesion mimicking a carcinoma

“…However common reported sites of origin of CCH are face, upper extremity, axilla, trunk, thigh, the ear Lobule, scalp and pubic region [4]. Although several skin adnexal tumors arise in the breast tissue, CCH of the breast is an extremely rare entity [3,4]. It usually manifests as an asymptomatic, solitary, firm, cutaneous nodule, measuring between 5 and 20 mm in diameter.…”

“…Rarely some lesions show squamous differentiation which is observed in our case. Furthermore, malignant transformation is possible but extremely rare [3] and has been observed in only few cases [4]. However, neither clinical behavior nor histological features can predict malignant change.…”

“…It can occur in case of inadequate excision. Compared to benign lesions malignant lesions has more tendencies to invade local tissue [3].…”

“…Eccrine hidradenoma's affected more frequently women than males [3]. It occurs commonly in middle-aged and older adults, and can be found anywhere on the body without predilection for a particular site [1].…”

Eccrine Hidradenoma of the Nasal Vestibule: A Rare Clinical Entity

“…3 The most common sites of involvement are the scalp, face, limbs, and anterior trunk, whereas eccrine hidradenoma involving the nose and paranasal sinuses is extremely rare. 1,4 Here, we report the first case of eccrine hidradenoma arising in the nasal vestibule. The tumor was completely removed using a transnasal endoscopic approach.…”