Clear Cell Carcinoma of the Base of the Tongue

Watanabe, Ken Ichi; Okumura, Yuri; Hashimoto, Ken; Suzuki, Takashi

doi:10.1177/0003489414542094

Cited by 12 publications

(8 citation statements)

References 24 publications

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“…HCCC characteristics were compared with other salivary gland carcinomas presenting to our institution using nonparametric Mann–Whitney U test for continuous variables, or Fisher exact test for dichotomous variables. Clinical outcomes of our cases combined with that of 99 reported HCCCs with available follow‐up from primary resection, were plotted using the Kaplan–Meier method. Duplicate (previously reported) cases were excluded.…”

Section: Methodsmentioning

confidence: 99%

Reappraising hyalinizing clear cell carcinoma: A population‐based study with molecular confirmation

et al. 2016

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Section: Methodsmentioning

confidence: 99%

Reappraising hyalinizing clear cell carcinoma: A population‐based study with molecular confirmation

et al. 2016

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“…The mean age in our series is 55 years (range 33-75) which is comparable to what is reported by others in literature. 1,6,13 The mean size of the excised tumour is documented to be 2.3 cm (range 1.1-3.9), making our case the largest diameter tumour documented in this series. Progressive dysphagia is the most common symptom on clinical presentation.…”

Section: Discussionmentioning

confidence: 61%

“…A total of 13 new cases were reported since 2015, including the case from our institution (Table 1). 3,[6][7][8][9][10][11][12] In total, there are 36 cases reported in literature since 1994. These numbers highlight the rarity of this tumour and resulting challenges in treatment selection.…”

Section: Discussionmentioning

confidence: 99%

Base of the tongue hyalinizing clear cell carcinoma: Case report and literature review

Al Zadjali,

Alsaffar,

Odell

et al. 2023

SAGE Open Medical Case Reports

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Hyalinizing clear cell carcinoma is an uncommon neoplasm arising in minor salivary glands. We present a rare case of hyalinizing clear cell carcinoma in the base of the tongue. We report a case of a 38-year-old female presented with a progressive history of hemoptysis and dysphagia over the course of 4 years. Examination revealed a mass originating from the base of the tongue with a biopsy confirmed as hyalinizing clear cell carcinoma . An Ovid MEDLINE and PubMed literature review was conducted due to the rarity of this type of tumor. The patient underwent surgical excision with immediate reconstruction with radial forearm free flap followed with adjuvant radiotherapy and was disease free at her most recent follow-up (12 months). Our review included a total of 13 new cases, including our case. The majority of the cases presented with dysphagia. Surgical excision is the mainstay of treatment, and overall these patients have a good prognosis. Our case highlights a rare presentation of hyalinizing clear cell carcinoma of the base of the tongue, successfully treated with surgical excision, free tissue reconstruction and adjuvant radiotherapy.

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“…However, surgical treatment of tongue cancer is often accompanied by postoperative complications, [ 10 , 11 ] including impaired mobility, logopathy, and ageusia. [ 12 – 15 ] Lymphadenectomy severely damages the superficial fascia during the dissection of subcutaneous lymph nodes.…”

Section: Discussionmentioning

confidence: 99%

Fu's subcutaneous needling for subcutaneous adhesions and scar hyperplasia in the neck region

Huang

Liu

et al. 2020

Medicine

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Rationale: Lymphadenectomy for tongue cancer in the neck region is often accompanied by local impaired mobility, gland damage, difficult in swallowing, and postoperative complication and seriously affects patients life quality. We reported a case of subcutaneous adhesions and scar hyperplasia in the neck region after lymphadenectomy for tongue lesions accompanied by impaired neck mobility and difficult in swallowing was treated using Fu's subcutaneous needling (FSN) treatment. Patient concerns: A 55-year-old male with tongue cancer received surgical intervention with lymphadenectomy 8 years ago was revealed a 15 cm-long curved surgical incision in the neck region and surrounded by numerous scar tissues. Diagnosis: Post-operation subcutaneous adhesions and scar hyperplasia in the neck region after lymphadenectomy was diagnosed. Interventions: FSN treatment was performed 2 to 3 times per week for 1 month to sway the affected tightened muscle and dissociate the superficial fascia beneath the scar resulted in a considerable improvement in neck movement. Outcomes: The Vancouver Scar Scale (VSS) was as follows: color (M) - 1; vascular distribution (V) - 0, thickness (H) - 2, and flexibility (P) - 4, with a total of 7 points before FSN treatment. The VSS after 1 month of FSN treatment was as follows: M1, V0, H2, and P2, with a total of 5 points. Neck mobility in different directions, i.e., stretching to the back of the neck and laterally bending the neck to the left and/or right side, was improved ( P < .05). Lessons: At present, treatment of chronic scar hyperplasia has certain side effects and limitations. FSN is safe and convenient, with minimal destruction of the superficial fascia, having evident effects of dissociating tissue adhesion under scars and compensating for deficiencies in scar hyperplasia treatment. It can provide new ideas for future treatments.

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Clear Cell Carcinoma of the Base of the Tongue

Abstract: We reveal the features of the unusual occurrence of CCC in the base of the tongue and consider the appropriate surgical approach for primary treatment.

Cited by 12 publications

References 24 publications

Reappraising hyalinizing clear cell carcinoma: A population‐based study with molecular confirmation

Reappraising hyalinizing clear cell carcinoma: A population‐based study with molecular confirmation

Base of the tongue hyalinizing clear cell carcinoma: Case report and literature review

Fu's subcutaneous needling for subcutaneous adhesions and scar hyperplasia in the neck region

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