Cleaning and decontamination of the healthcare environment

Dancer, S.J.

doi:10.1533/9780857096692.2.370

Cited by 5 publications

(4 citation statements)

References 185 publications

(293 reference statements)

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“…A. tumefaciens originates in plants and soil [28,29]. S. maltophilia frequently colonizes humid abiotic surfaces in water installations, mechanical ventilation systems and medical devices [30], as do A. hydrophila [31,32,33] and J. lividum , which are often isolated from water and water-living animals [34]. S. maltophilia is closely related to Pseudomonas and Xanthomonas genera.…”

Section: Resultsmentioning

confidence: 99%

Antimicrobial and Antibiofilm N-acetyl-L-cysteine Grafted Siloxane Polymers with Potential for Use in Water Systems

Kręgiel

Rygała

Kolesińska

et al. 2019

IJMS

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Antibiofilm strategies may be based on the prevention of initial bacterial adhesion, the inhibition of biofilm maturation or biofilm eradication. N-acetyl-L-cysteine (NAC), widely used in medical treatments, offers an interesting approach to biofilm destruction. However, many Eubacteria strains are able to enzymatically decompose the NAC molecule. This is the first report on the action of two hybrid materials, NAC-Si-1 and NAC-Si-2, against bacteria isolated from a water environment: Agrobacterium tumefaciens, Aeromonas hydrophila, Citrobacter freundii, Enterobacter soli, Janthinobacterium lividum and Stenotrophomonas maltophilia. The NAC was grafted onto functional siloxane polymers to reduce its availability to bacterial enzymes. The results confirm the bioactivity of NAC. However, the final effect of its action was environment- and strain-dependent. Moreover, all the tested bacterial strains showed the ability to degrade NAC by various metabolic routes. The NAC polymers were less effective bacterial inhibitors than NAC, but more effective at eradicating mature bacterial biofilms.

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Section: Resultsmentioning

confidence: 99%

Antimicrobial and Antibiofilm N-acetyl-L-cysteine Grafted Siloxane Polymers with Potential for Use in Water Systems

Kręgiel

Rygała

Kolesińska

et al. 2019

IJMS

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“…CaMV can also be transmitted mechanically by sap inoculation using contaminated hands and pruning tools (Yasaka et al, 2014). It has been shown that CaMV can stay for hours on surfaces such as doors, phones, and gloves, and can be exchanged by hand-shaking (Jiang et al, 1998;Dancer, 2014), so disinfecting tools, equipment, and anything that contacts plants will reduce infection. Though it did not include CaMV, a study that tested how to prevent propagation of plant viruses, such as Pepino mosaic virus (PepMV), Potato spindle tuber viroid (PSTVd), Tomato mosaic virus (ToMV), and Tobacco mosaic virus (TMV), examined sixteen commercially available disinfectants and found that 10% bleach is the most effective solution for preventing viral infection of plants in greenhouse facilities (Li et al, 2015).…”

Section: Camv In Agriculture and Management Practices To Reduce Camv mentioning

confidence: 99%

Cauliflower mosaic virus (CaMV) Biology, Management, and Relevance to GM Plant Detection for Sustainable Organic Agriculture

Bak

Emerson

2020

Front. Sustain. Food Syst.

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In today's global market, some organic farmers must meet regulatory requirements to demonstrate that their plants and feedstocks are genetically modified organism (GMO)-free. Many GM plants are engineered to contain a promoter from the plant virus, Cauliflower mosaic virus (CaMV), in order to facilitate expression of an engineered target gene. The relative ubiquity of this CaMV 35S promoter (P35S) in GM constructs means that assays designed to detect GM plants often target the P35S DNA sequence, but these detection assays can yield false-positives from plants that are infected by naturally-occurring CaMV or its relatives within the Caulimoviridae. This review places CaMV infection and these ambiguous GM plant detection assays in context, serving as a resource for industry professionals, regulatory bodies, and researchers at the nexus of organic farming and global commerce. We first briefly introduce GM plants from a regulatory perspective, and then we describe CaMV biology, transmission, and management practices, highlighting the relatively widespread nature of CaMV infection in both GM and non-GM crops within the Brassicaceae and Solanaceae families. Finally, we discuss current knowledge of public food safety related to the consumption of CaMV-infected produce.

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“…Essentially, disinfection keeps surfaces in hospital environments void of pathogens from the surrounding environments [7]. However, despite the various efforts made by healthcare workers to keep these environments sterile [8,9], such surfaces, whether constantly touched or not, are often contaminated. Reports have revealed the presence of such bacterial organisms as methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), Streptococcus pyogenes, Pseudomonas aeruginosa, Acinetobacter sp, Escherichia coli, Serratia marcescens, Shigella sp, Klebsiella pneumonia, Salmonella sp, Citrobacter sp and Yersinia sp.…”

Section: Introductionmentioning

confidence: 99%

Antibiogram Profile of Enteric Pathogens Isolated from Fomites in Cross River University of Technology Medical Centre, Calabar, Nigeria

Bassey

Tarh

Otu

et al. 2022

ARRB

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Background: Healthcare environments are considered as potential reservoirs for pathogenic microorganisms especially those responsible for nosocomial infections. Such microorganisms often present with varying degrees of drugs resistance. This study was aimed at evaluating the Cross River University of Technology (CRUTECH) Medical Center Environment for the presence of pathogenic bacterial contaminants and antibiotics susceptibility profile of such isolates. Materials and Methodology: A total of 72 swab samples were collected from nineteen frequently touched hospital surfaces and processed using the standard bacteriological procedures. The emergent bacterial colonies were identified using phenotypic and biochemical tests. Antibiotic susceptibility testing of the presumptively identified isolates was carried out using Kirby-Bauer’s method. Results: Out of 72 swab samples collected, 44 (61.1%) were positive for Enteric bacterial pathogens. The mean viable count ranged from 1.8 x 106 Cfu/cm2 (weighing scales) to 2.41 x 107 Cfu/cm2 (wash sinks). The most prevalent isolate was E. coli (48 of 127, 37.8%) followed by Klebseilla sp (27 of 127, 21.3%), Salmonella sp (19 of 127, 14.9%), Proteus sp (12 of 127, 9.4%), Citrobacter sp (11 of 127, 8.7%), Enterobacter sp (7 of 127, 5.5%) while Shigella sp (3 of 127, 2.4%) was least isolated. Isolates demonstrated high level of susceptibility to Norfloxacin 124 (97.6%), Imipenem 116 (91.3%) and Chloramphenicol 105 (82.7%). Resistance to Erythromycin was 95 (74.8%), Gentamycin 84 (66.1%) and Amikacin 82 (64.6%). Conclusion: Contamination of healthcare surfaces by multi-drugs resistant pathogens is a potential risk, especially to hospitalized patients and health care workers. Thus, it is therefore imperative that appropriate hygienic measures be implemented to suppress any potential microbial cross-contamination.

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Cleaning and decontamination of the healthcare environment

Cited by 5 publications

References 185 publications

Antimicrobial and Antibiofilm N-acetyl-L-cysteine Grafted Siloxane Polymers with Potential for Use in Water Systems

Antimicrobial and Antibiofilm N-acetyl-L-cysteine Grafted Siloxane Polymers with Potential for Use in Water Systems

Cauliflower mosaic virus (CaMV) Biology, Management, and Relevance to GM Plant Detection for Sustainable Organic Agriculture

Antibiogram Profile of Enteric Pathogens Isolated from Fomites in Cross River University of Technology Medical Centre, Calabar, Nigeria

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