Classification of potential pathways affecting the VEGF pathway in glioblastoma multiforme (GBM) recurrent: A bioinformatics study based on differentially expressed- microRNAs
Abstract:Glioblastoma multiforme (GBM) resistance to anti-angiogenesis drugs results in recurrence of the disease which leads to death. The resistance to anti-angiogenesis drugs that target the VEGF pathway is due to the influence of other pathways. This study aimed to identify and classify the pathways that are related to the VEGF pathway in GBM recurrent. The identification of differentially expressed miRNAs (DEmiRNAs) based on GBM GSE profiles (GSE32466) were carried out using a LIMMA R package and VEGF pathway gene… Show more
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