“…These methods are not exclusive for MR imaging, and they can be used with other imaging techniques ( Segovia et al, 2017a , b ; Ortiz et al, 2019 ) and even with clinical, molecular, and genetic biomarkers applied to build a model of the pathology ( Latourelle et al, 2017 ). Some examples on this approach highlighting the benefits of this computer aided diagnosis (CAD) systems analysis is beyond the scope of this review but it’s worth mentioning some works as the following ( Sengur et al, 2017 ; van der Burgh et al, 2017 ; Martinez-Murcia et al, 2018 ; Yamashita et al, 2018 ).…”