Classification criteria for Sjogren’s syndrome: A critical review

Baldini, Chiara; Talarico, Rosaria; Tzioufas, Athanasios G.; Bombardieri, Stefano

doi:10.1016/j.jaut.2011.12.006

Cited by 114 publications

(82 citation statements)

References 29 publications

(43 reference statements)

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“…Sjögren's syndrome is an autoimmune disorder of the connective tissue leading to the reduction of secretory functions of salivary and lacrimal glands [1,2]. The disease affects nearly 1.7 million people in the European Union and around 1 million people in the United States (~90% of them are middle-aged women) [3].…”

Section: Introductionmentioning

confidence: 99%

Quantitative assessment of oral mucosa and labial minor salivary glands in patients with Sjögren’s syndrome using swept source OCT

Grulkowski

Nowak

Karnowski

et al. 2013

Biomed. Opt. Express

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Three-dimensional imaging of the mucosa of the lower lip and labial minor salivary glands is demonstrated in vivo using swept source optical coherence tomography (OCT) system at 1310 nm with modified interface. Volumetric data sets of the inner surface of the lower lip covering ~230 mm 2 field are obtained from patients with Sjögren's syndrome and a control group. OCT enables high-resolution visualization of mucosal architecture using cross-sectional images as well as en-face projection images. Comprehensive morphometry of the labial minor salivary glands is performed, and statistical significance is assessed. Statistically significant differences in morphometric parameters are found when subgroups of patients with Sjögren's syndrome are analyzed.

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Section: Introductionmentioning

confidence: 99%

Quantitative assessment of oral mucosa and labial minor salivary glands in patients with Sjögren’s syndrome using swept source OCT

Grulkowski

Nowak

Karnowski

et al. 2013

Biomed. Opt. Express

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show abstract

“…Sjogren's syndrome has a wide clinical and immunologic spectrum and may progress from an exocrinopathy to a systemic disease with a variety of extraglandular manifestations and/ or associated autoimmune diseases. The difficulty in diagnosis is reflected on continuous review attempts of the 7 classification criteria that have been created in the past 25 years [13]. However, histological analysis of labial salivary gland biopsy (LSGB) is mostly a method of great importance according to the American-European Group Consensus (AEGC) criteria [14].…”

Section: Case Reportmentioning

confidence: 99%

Sjögren’s Syndrome - Oral Changes, Advanced Diagnosis, and Management - A Case Report

Minic¹,

A²,

Pesic³

et al. 2016

Journal of Case Reports and Studies

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“…Sjögren's syndrome (SS) is a chronic, systemic autoimmune disorder which affects typically the exocrine glands associated with/ without every other systemic autoimmune rheumatic disorder [1,2]. The ocular and oral dryness can be caused by a typical focal lymphocytic infiltration of the lacrimal and salivary glands [1].…”

Section: Introductionmentioning

confidence: 99%

“…The ocular and oral dryness can be caused by a typical focal lymphocytic infiltration of the lacrimal and salivary glands [1]. Its wide clinical spectrum includes not only benign local exocrinopathy (dry eyes, dry mouth) but also systemic disorder that affects parenchymal organs (liver, kidneys, lung), lesions owing to immune complex hyperproduction and/or vasculitic involvement (glomerulonephritis, peripheral neuropathy, purpura), and lymphocytic malignancies which is known to occur in 5% of SS patients [3].…”

Section: Introductionmentioning

confidence: 99%

“…Thus, SS can be regarded as a heterogeneous autoimmune disease with both organ-specific and systemic features, and showing a wide variety of clinical/serological abnormalities with scattered complications [4,5]. Due to such complexity, it has been difficult to identify a homogeneous group of patients sharing a common etiopathogenesis or prognosis and finally to develop classification/diagnostic criteria for the disease [1]. This also can be explained in the several different classification criteria sets for SS proposed by leading experts in the field over the years [6][7][8].…”

Section: Introductionmentioning

confidence: 99%

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Ocular Manifestations of Sjögren Syndrome

Song

Lee

2016

Hanyang Med Rev

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Sjögren Syndrome (SS) is one of the most frequent systemic autoimmune disorders, mainly involving the eye and mouth due to inflammation of lacrimal and salivary glands. Exocrine glands affected with a typical focal lymphocytic infiltration potentially lead to dry eyes and dry mouth. In addition to the known pathogenic mechanism of SS through autoimmunity, corneal neuropathy, as a peripheral neuropathy which is a relatively frequent extraglandular systemic manifestation of SS, recently draws attention as a possible pathogenic mechanism of ocular symptoms and dry eye induction. The diagnostic criteria of SS changed recently, proposed by the American College of Rheumatology/Sjögren's International Collaborative Clinical Alliance (ACR/SICCA) in 2012, and the ocular surface staining score is the only required test for ocular manifestation of SS. However, other diagnostic methods evaluating tear film status, though excluded from the new criteria, are still important for the staging and treatment planning, including direct observation of tear film, tear film break up time, Schirmer test, and measurement of the tear film levels of inflammatory mediators. Eye-specific symptoms and signs and ocular treatment options for SS including tear substitutes, secretogogue, topical anti-inflammatory therapy with corticosteroids and cyclosporine, punctal occlusion, autologous serum, and mucolytic therapy were summarized and discussed in this review article.

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Classification criteria for Sjogren’s syndrome: A critical review

Cited by 114 publications

References 29 publications

Quantitative assessment of oral mucosa and labial minor salivary glands in patients with Sjögren’s syndrome using swept source OCT

Quantitative assessment of oral mucosa and labial minor salivary glands in patients with Sjögren’s syndrome using swept source OCT

Sjögren’s Syndrome - Oral Changes, Advanced Diagnosis, and Management - A Case Report

Ocular Manifestations of Sjögren Syndrome

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