Seriation is the practice of performing row and column permutations on data matrices to reveal clusters and hidden patterns within and between them. Seriation has been a known problem to tackle in the literature for over a century except chemical data where there are a fewer than a handful of researchers who have knowingly worked on this technique. The aim of this paper is to give seriation examples on chemical data and to propose the systematic use of seriation as a possible intuitive tool between data preprocessing and explanatory data analysis. Seriation itself performs the descriptive and exploratory data evaluations at a qualitative level with more limited efficiency than the specialized methods, but it may suggest to use clustering, variable selection, principal component analysis, and modeling. Different databases were used to check the versatility of seriation methods: benchmark ones on iris and wine, radioactivity data of sand mines, coin metal compositions, bioactivity of anticancer compounds, features of essential oils, and a reaction kinetic mechanism of biofuel combustion.