Classical and Innovative Evidence for Therapeutic Strategies in Retinal Dysfunctions
Lorenzo Caruso,
Matteo Fields,
Erika Rimondi
et al.
Abstract:The human retina is a complex anatomical structure that has no regenerative capacity. The pathogenesis of most retinopathies can be attributed to inflammation, with the activation of the inflammasome protein platform, and to the impact of oxidative stress on the regulation of apoptosis and autophagy/mitophagy in retinal cells. In recent years, new therapeutic approaches to treat retinopathies have been investigated. Experimental data suggest that the secretome of mesenchymal cells could reduce oxidative stress… Show more
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