Classic and exertional heatstroke

Bouchama, Abderrezak; Abuyassin, Bisher; Lehé, Cynthia; Laitano, Orlando; Jay, Ollie; O’Connor, Francis G.; Leon, Lisa R.

doi:10.1038/s41572-021-00334-6

Cited by 138 publications

(136 citation statements)

References 307 publications

Supporting

Mentioning

133

Contrasting

Order By: Relevance

“…The critical thermal maximum in humans is a body temperature of 42 °C lasting for few hours. Due to the ongoing climate change, the mortality due to heat strokes is expected to increase [20] . At extreme temperatures (49 °C to 50 °C), all cellular structures are destroyed and cellular necrosis occurs in less than five minutes.…”

Section: The Relevant Range Of Temperaturesmentioning

confidence: 99%

The life and death of RNA across temperatures

Becskei

Rahaman

2022

Computational and Structural Biotechnology Journal

View full text Add to dashboard Cite

Section: The Relevant Range Of Temperaturesmentioning

confidence: 99%

The life and death of RNA across temperatures

Becskei

Rahaman

2022

Computational and Structural Biotechnology Journal

View full text Add to dashboard Cite

“…• ↓ Intestinal permeability (Butler-Dawson et al, 2019;Gan et al, 2022;King et al, 2016) • ↓ Cytokinaemia (Bouchama et al, 2022;Ogden et al, 2021) • ↑ Leukocyte function (Bouchama et al, 2022) • ↑ Central drive and ↓ perceived effort may increase EHS risk (Carter et al, 2007) • Large doses may induce GI symptoms (Dong et al, (Roberts et al, 2021;Zuhl et al, 2015;Zuhl et al, 2014) • Higher doses may induce GI symptoms (Parker et al, 2018) • No beneficial effect at low doses (Peel et al, 2021;Roberts et al, 2021) Bovine colostrum 20 g day −1 for 14 days…”

Section: Potential Mechanisms Of Protection Against Ehs Considerationsmentioning

confidence: 99%

Exertional heat stroke: nutritional considerations

Lee

Tan

Ogden

et al. 2022

Experimental Physiology

View full text Add to dashboard Cite

Exertional heat stroke (EHS) is a life-threatening illness and an enduring problem among athletes, military servicemen and -women, and occupational labourers who regularly perform strenuous activity, often under hot and humid conditions or when wearing personal protective equipment. Risk factors for EHS and mitigation strategies have generally focused on the environment, health status, clothing, heat acclimatization and aerobic conditioning, but the potential role of nutrition is largely underexplored. Various nutritional and dietary strategies have shown beneficial effects on exercise performance and health and are widely used by athletes and other physically active populations. There is also evidence that some of these practices may dampen the pathophysiological features of EHS, suggesting possible protection or abatement of injury severity. Promising candidates include carbohydrate ingestion, appropriate fluid intake and glutamine supplementation. Conversely, some nutritional factors and low energy availability may facilitate the development of EHS, and individuals should be cognizant of these. Therefore, the aims of this review are to present an overview of EHS along with its mechanisms and pathophysiology, discuss how selected nutritional considerations may influence EHS risk focusing on their impactThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

show abstract

“…Climate change is projected to increase global ambient temperatures and increase the frequency, intensity, and duration of heat waves (Haines et al, 2006 ; Romanello et al, 2021 ). The higher means and extremes of ambient temperatures will particularly challenge (elite) athletes, as prolonged exercise, especially under heat stress, can produce profound elevations in core temperature (T c ) (Racinais et al, 2019 ), potentially leading to attenuated exercise performance (de Korte et al, 2021a ) and an increased risk for heat-related illnesses (American College of Sports Medicine et al, 2007 ; Epstein and Roberts, 2011 ; Casa et al, 2015 ; Periard et al, 2021 ; Bouchama et al, 2022 ). Exertional heat illness can vary from mild complaints such as exercise-associated muscle cramps, to more serious concerns such as heat syncope and heat exhaustion, and can also become life threatening during a heat stroke.…”

Section: Introductionmentioning

confidence: 99%

A Heart Rate Based Algorithm to Estimate Core Temperature Responses in Elite Athletes Exercising in the Heat

Korte¹,

Veenstra²,

Rijswick³

et al. 2022

Front. Sports Act. Living

View full text Add to dashboard Cite

PurposeNon-invasive non-obtrusive continuous and real-time monitoring of core temperature (Tc) may enhance pacing strategies, the efficacy of heat mitigation measures, and early identification of athletes at risk for heat-related disorders. The Estimated Core Temperature (ECTemp™) algorithm uses sequential heart rate (HR) values to predict Tc. We examined the validity of ECTemp™ among elite athletes exercising in the heat.Methods101 elite athletes performed an exercise test in simulated hot and humid environmental conditions (ambient temperature: 31.6 ± 1.0°C, relative humidity: 74 ± 5%). Tc was continuously measured using a validated ingestible telemetric temperature capsule system. In addition, HR was continuously measured and used to compute the estimated core temperature (Tc−est) using the ECTemp™ algorithm.ResultsAthletes exercised for 44 ± 10 min and n = 5,025 readouts of Tc (range: 35.8–40.4°C), HR (range: 45–207 bpm), and Tc−est (range: 36.7–39.9°C) were collected. Tc−est demonstrated a small yet significant bias of 0.15 ± 0.29°C (p < 0.001) compared to Tc, with a limit of agreement of ±0.45°C and a root mean square error of 0.35 ± 0.18°C. Utilizing the ECTemp™ algorithm as a diagnostic test resulted in a fair to excellent sensitivity (73–96%) and specificity (72–93%) for Tc−est thresholds between 37.75 and 38.75°C, but a low to very-low sensitivity (50–0%) for Tc−est thresholds >39.0°C, due to a high prevalence of false-negative observations.ConclusionECTemp™ provides a valuable and representative indication of thermal strain in the low- to mid-range of Tc values observed during exercise in the heat. It may, therefore, be a useful non-invasive and non-obtrusive tool to inform athletes and coaches about the estimated core temperature during controlled hyperthermia heat acclimation protocols. However, the ECTemp™ algorithm, in its current form, should not solely be used to identify athletes at risk for heat-related disorders due to low sensitivity and high false-negative rate in the upper end of the Tc spectrum.

show abstract

Classic and exertional heatstroke

Cited by 138 publications

References 307 publications

The life and death of RNA across temperatures

The life and death of RNA across temperatures

Exertional heat stroke: nutritional considerations

A Heart Rate Based Algorithm to Estimate Core Temperature Responses in Elite Athletes Exercising in the Heat

Contact Info

Product

Resources

About