The quantum (or
q
-) calculus is widely applied in various operators which include the
q
-difference (
q
-derivative) operator, and this operator plays an important role in geometric function theory (GFT) as well as in the theory of hypergeometric series. In our present investigation, we introduce and study
q
-differential operator associated with
q
-Mittag–Leffler function which is an extension of the Salagean
q
-differential operator. By using this newly defined operator, we define a new subclass of analytic function and studied certain subclass of analytic function in generalized conic domain
Ω
k
,
q
,
γ
. For this class, we investigate structural formula, coefficient estimates, sufficient condition, Fekete–Szegö problem, and also some subordination results.