Clarifying the Role of Neural Networks in Complex Hallucinatory Phenomena

O’Callaghan, Claire; Muller, Alana J.; Shine, James M.

doi:10.1523/jneurosci.2429-14.2014

Cited by 2 publications

(2 citation statements)

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“…It follows that abnormal activity in these input zones could conceivably produce the combination of visual, autobiographical, and emotive qualities that characterise complex visual hallucinations (O’Callaghan, Muller, & Shine, 2014). Importantly, the emergence of hallucinatory phenomena with abnormal activity in these sites has been verified independently in direct electrical stimulation studies conducted during neurosurgery.…”

Section: Visual Hallucinationsmentioning

confidence: 99%

Predictions penetrate perception: Converging insights from brain, behaviour and disorder

O’Callaghan

Kveraga

Shine

et al. 2017

Consciousness and Cognition

143

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It is argued that during ongoing visual perception, the brain is generating top-down predictions to facilitate, guide and constrain the processing of incoming sensory input. Here we demonstrate that these predictions are drawn from a diverse range of cognitive processes, in order to generate the richest and most informative prediction signals. This is consistent with a central role for cognitive penetrability in visual perception. We review behavioural and mechanistic evidence that indicate a wide spectrum of domains—including object recognition, contextual associations, cognitive biases and affective state—that can directly influence visual perception. We combine these insights from the healthy brain with novel observations from neuropsychiatric disorders involving visual hallucinations, which highlight the consequences of imbalance between top-down signals and incoming sensory information. Together, these lines of evidence converge to indicate that predictive penetration, be it cognitive, social or emotional, should be considered a fundamental framework that supports visual perception.

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Section: Visual Hallucinationsmentioning

confidence: 99%

Predictions penetrate perception: Converging insights from brain, behaviour and disorder

O’Callaghan

Kveraga

Shine

et al. 2017

Consciousness and Cognition

143

View full text Add to dashboard Cite

show abstract

“…If we examine the possible origins of the visual hallucinations under the predictive umbrella, we could hypothesize that higher levels are mostly represented by the DMN ( O'Callaghan et al, 2014 ). Thus, its disruption could determine an intrusion of the episodic memory in the perceptive system through top-down processes, as suggested by an overactivity within the DMN and by a dysregulated FC between the DMN and other networks.…”

Section: Discussionmentioning

confidence: 99%