Claim for a new paradigm of hospital physicians: Evolution along 13 years in an acute internal medicine ward in Portugal

Lopes, Franccesca; Dias, A.R.; Miranda, A; Alves, Maria Virgínia Martins Faddul; Narciso, Michelle; Fonseca, T; Clara, J. Gorjão

doi:10.1016/j.eurger.2013.07.080

Cited by 1 publication

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“…In some systems, where older people are regularly seen by geriatricians, they will see most cases, while in others, only ‘complicated’ cases will be referred to geriatricians or will be hospitalized under their care. Geriatricians are often faced with older patients who have longer and more severe HZ-associated pain and who, on average, can have about five comorbidities at 65 years increasing to almost seven at 85 years [Lopes et al 2013; Miranda et al 2013]. PHN and its treatment can affect the cardiovascular system (increased heart rate and blood pressure, hypercoagulation leading to an increased risk of deep vein thrombosis and pulmonary embolism), the gastrointestinal system (delayed gastric emptying and reduced bowel motility), respiratory dysfunction (leading to hypoxia and cardiac complications), retention of sodium and water (resulting in urine retention, increased cardiac workload and hypertension) [Bruckenthal et al 2013; Lopes et al 2013; Miranda et al 2013; Sacks, 2013].…”

Section: Multidisciplinary Perspectives Of Clinical Manifestations Anmentioning

confidence: 99%

Herpes zoster epidemiology, management, and disease and economic burden in Europe: a multidisciplinary perspective

Johnson

Álvarez-Pasquín

Bijl

et al. 2015

Therapeutic Advances in Vaccines

193

126

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Herpes zoster (HZ) is primarily a disease of nerve tissue but the acute and longer-term manifestations require multidisciplinary knowledge and involvement in their management. Complications may be dermatological (e.g. secondary bacterial infection), neurological (e.g. long-term pain, segmental paresis, stroke), ophthalmological (e.g. keratitis, iridocyclitis, secondary glaucoma) or visceral (e.g. pneumonia, hepatitis). The age-related increased incidence of HZ and its complications is thought to be a result of the decline in cell-mediated immunity (immunosenescence), higher incidence of comorbidities with age and social-environmental changes. Individuals who are immunocompromised as a result of disease or therapy are also at increased risk, independent of age. HZ and its complications (particularly postherpetic neuralgia) create a significant burden for the patient, carers, healthcare systems and employers. Prevention and treatment of HZ complications remain a therapeutic challenge despite recent advances. This is an overview of the multidisciplinary implications and management of HZ in which the potential contribution of vaccination to reducing the incidence HZ and its complications are also discussed.

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Section: Multidisciplinary Perspectives Of Clinical Manifestations Anmentioning

confidence: 99%

Herpes zoster epidemiology, management, and disease and economic burden in Europe: a multidisciplinary perspective

Johnson

Álvarez-Pasquín

Bijl

et al. 2015

Therapeutic Advances in Vaccines

193

126

View full text Add to dashboard Cite

show abstract

Claim for a new paradigm of hospital physicians: Evolution along 13 years in an acute internal medicine ward in Portugal

Cited by 1 publication

References 0 publications

Herpes zoster epidemiology, management, and disease and economic burden in Europe: a multidisciplinary perspective

Herpes zoster epidemiology, management, and disease and economic burden in Europe: a multidisciplinary perspective

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